Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Benzil. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 known ✓ | P09874 | 1/20 | 0.55 |
| ▸ | MEN1 known ✓ | O00255 | 1/20 | 0.52 |
| ▸ | CES2 | O00748 | 12/20 | 0.93 |
| ▸ | CES1 | P23141 | 12/20 | 0.93 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | DAO | P14920 | 1/20 | 0.61 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | CA4 | P22748 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzil SCHEMBL27539146 | 1.00 | CES2 (0.93) | CES2CES1TSHRDAONAPRT | |
| Benzil SCHEMBL28475956 | 0.97 | CES2 (1.00) | CES2CES1TSHRDAONAPRT | |
| Benzil SCHEMBL2156589 | 0.97 | CES2 (1.00) | CES2CES1TSHRDAONAPRT | |
| Benzil SCHEMBL9517636 | 0.97 | CES2 (1.00) | CES2CES1TSHRDAONAPRT | |
| Benzil SCHEMBL7142843 | 0.97 | CES2 (1.00) | CES2CES1TSHRDAONAPRT | |
| Benzil SCHEMBL66 | 0.97 | CES2 (1.00) | CES2CES1TSHRDAONAPRT | |
| Benzil SCHEMBL1002038 | 0.93 | CES2 (0.93) | CES2CES1TSHRDAONAPRT | |
| Benzil SCHEMBL4957522 | 0.93 | CES2 (1.00) | CES2CES1TSHRDAONAPRT | |
| Benzil SCHEMBL10996187 | 0.93 | CES2 (0.93) | CES2CES1TSHRDAONAPRT | |
| Benzil SCHEMBL1311689 | 0.93 | CES2 (0.93) | CES2CES1TSHRDAONAPRT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109536087-A | Optics pressure sensitive adhesive and preparation method thereof | 苏州凡赛特材料科技有限公司 | 2019-03-29 | — | — | CN | claimed |
| US-5082914-A | Solvent resistant hard protective coating | EASTMAN KODAK COMPANY (US) | 1992-01-21 | — | — | US | claimed |
| CN-117835533-A | Photosensitive element, laminate, method for producing same, method for forming resist pattern, and method for producing printed wiring board | 株式会社力森诺科 | 2024-04-05 | — | — | CN | disclosed |
| CN-117229496-A | Amphiphilic alternating main chain polymer containing benzil phosphorescent groups and preparation method thereof | 华东理工大学 | 2023-12-15 | — | — | CN | disclosed |
| CN-116444702-A | Preparation method of polyisobutene oil for viscosity standard substance | 山东非金属材料研究所 | 2023-07-18 | — | — | CN | disclosed |
| CN-110511022-A | A kind of high solid loading zirconia ceramics creme and preparation method, and structural member and preparation method based on it | NAT INSTITUTE CORPORATION OF ADDITIVE MANUFACTURING XIAN | 2019-11-29 | — | — | CN | disclosed |
| CN-109810638-A | A kind of low-refraction optics pressure sensitive adhesive and its preparation method and application | 苏州凡赛特材料科技有限公司 | 2019-05-28 | — | — | CN | disclosed |
| CN-105037629-A | Silicone hydrogel with good resilience and preparation method and application method therefor | UNIV SOUTHEAST | 2015-11-11 | — | — | CN | disclosed |
| CN-102675561-B | silicone hydrogel with high water content | FAR EASTERN NEW CENTURY CORPORATION (CN) | 2014-10-22 | — | — | CN | disclosed |
| CN-102115515-B | Copolymer for improving wettability of silicone hydrogel, silicone hydrogel composition containing same and ophthalmic article prepared therefrom | FAR EASTERN NEW CENTURY CORP | 2014-06-18 | — | — | CN | disclosed |
| US-20140044962-A1 | ADHESIVE COMPOSITION, FILM ADHESIVE, AND BONDING METHOD | TOKYO OHKA KOGYO CO., LTD. (JP) | 2014-02-13 | — | — | US | disclosed |
| CN-102675561-A | Silicone hydrogel with high water content | FAR EASTERN NEW CENTURY CORP | 2012-09-19 | — | — | CN | disclosed |
| CN-102675658-A | Method for preparing polysiloxane hydrogel with high moisture content | FAR EASTERN NEW CENTURY CORP | 2012-09-19 | — | — | CN | disclosed |
| CN-102464744-A | Chlorinated polymers that enhance wettability of silicone hydrogels, silicone hydrogels comprising the same, and ophthalmic articles made therefrom | FAR EASTERN NEW CENTURY CORP | 2012-05-23 | — | — | CN | disclosed |
| CN-102115515-A | Copolymer for improving wettability of silicone hydrogel, silicone hydrogel composition containing same and ophthalmic article prepared therefrom | FAR EASTERN NEW CENTURY CORP | 2011-07-06 | — | — | CN | disclosed |
| EP-0854024-B1 | Thin-film fabrication method and apparatus | NAT INST OF ADVANCED IND SCIEN (JP) | 2002-09-18 | — | — | EP | disclosed |
| US-6319321-B1 | Thin-film fabrication method and apparatus | AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY MINISTRY OF INTERNATIONAL TRADE & INDUSTRY (JP) | 2001-11-20 | — | — | US | disclosed |
| CN-1074705-C | Coated abrastive article and method of making same | MINNESOTA MINING & MFG (US) | 2001-11-14 | — | — | CN | disclosed |
| EP-0854024-A2 | Thin-film fabrication method and apparatus | Agency of Industrial Science and Technology of Ministry of International Trade and Industry (JP) | 1998-07-22 | — | — | EP | disclosed |
| CN-1074637-A | Coated abrasive article and preparation method thereof | MINNESOTA MINING & MFG (US) | 1993-07-28 | — | — | CN | disclosed |