Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9483528 | 0.73 | NR1H2 (0.35) | GPR3KCNH2CNR1PTPN1MEN1 | |
| SCHEMBL9483541 | 0.73 | NR1H2 (0.35) | GPR3KCNH2CNR1PTPN1MEN1 | |
| SCHEMBL8595375 | 0.70 | — | — | |
| SCHEMBL4788655 | 0.70 | KCNH3 (0.38) | PTPN1NPC1ALDH1A1 | |
| SCHEMBL2364518 | 0.67 | GABRA1 (0.54) | CNR1PTPN1MEN1KMT2AATM | |
| SCHEMBL30030411 | 0.66 | IDO1 (0.32) | KMT2A | |
| SCHEMBL3259331 | 0.63 | ACHE (0.43) | KCNH2PTPN1MEN1KMT2AALDH1A1 | |
| SCHEMBL5601077 | 0.62 | KCNH2 (0.39) | GPR3KCNH2CNR1PTPN1NR1H2 | |
| SCHEMBL5602197 | 0.61 | GPR3 (0.42) | GPR3KCNH2CNR1PTPN1NR1H2 | |
| SCHEMBL16486471 | 0.61 | MAPT (0.34) | MEN1KMT2AALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020151543-A1 | Compositions and methods employing R (-) fluoxetine and other active ingredients | SEPRACOR INC. | 2002-10-17 | — | — | US | disclosed |
| WO-2000024399-A1 | COMPOSITIONS AND METHODS EMPLOYING R(-) FLUOXETINE AND OTHER ACTIVE INGREDIENTS | SEPRACOR INC. (US) | 2000-05-04 | — | — | WO | disclosed |