SCHEMBL7572822

SCHEMBL7572822

Cc1ccc(S(=O)(=O)Oc2cccc(C)c2C)cc1

nearest known ligand 0.59

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.59
KMT2A Q03164 5/20 0.59
ESR1 P03372 2/20 0.59
GAA P10253 2/20 0.59
ESR2 Q92731 2/20 0.59
HTR6 P50406 6/20 0.57
LMNA P02545 2/20 0.52
MAPK1 P28482 1/20 0.52
ALDH1A1 P00352 4/20 0.50
MAPT P10636 4/20 0.50
NPSR1 Q6W5P4 1/20 0.50
KEAP1 Q14145 1/20 0.45
NFE2L2 Q16236 1/20 0.45
VDR P11473 1/20 0.45
HTT P42858 1/20 0.44
CYP1A2 P05177 1/20 0.43
KDM4E B2RXH2 1/20 0.42
HPGD P15428 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31555138 1.00 MEN1 (0.59) MEN1KMT2AESR1GAAESR2
Hydrogen Sulfide SCHEMBL5918505 0.98 MEN1 (0.57) MEN1KMT2AESR1GAAESR2
SCHEMBL15121444 0.87 MEN1 (0.52) MEN1KMT2AESR1GAAESR2
SCHEMBL29586241 0.86 LMNA (0.59) MEN1KMT2AESR1GAAESR2
SCHEMBL3824499 0.86 LMNA (0.59) MEN1KMT2AESR1GAAESR2
SCHEMBL15442140 0.83 KMT2A (0.56) MEN1KMT2AESR1GAAESR2
SCHEMBL27410723 0.83 KMT2A (0.56) MEN1KMT2AESR1GAAESR2
SCHEMBL13605945 0.83 KMT2A (0.64) MEN1KMT2AESR1GAAESR2
SCHEMBL64533 0.82 KMT2A (0.62) MEN1KMT2AESR1GAAESR2
SCHEMBL19509226 0.81 LMNA (0.55) MEN1KMT2AESR1GAAESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260072035-A1 ENHANCED SPECIFICITY MASS TAG DNA ADDUCTOMICS UNIV NORTHEASTERN (US) 2026-03-12 US claimed
EP-4511513-A1 ENHANCED SPECIFICITY MASS TAG DNA ADDUCTOMICS Northeastern University (US) 2025-02-26 EP claimed
WO-2023239572-A1 ENHANCED SPECIFICITY MASS TAG DNA ADDUCTOMICS NORTHEASTERN UNIVERSITY (US) 2023-12-14 WO claimed
CN-119452026-A Cellulose ester polymer compositions having low coefficient of friction 乐高公司 2025-02-14 CN disclosed
CN-113527101-B Novel compound, polymer, process for producing the same, photosensitive resin composition, pattern forming process, cured film, and electronic component 信越化学工业株式会社 2024-04-23 CN disclosed
CN-113527680-B Polymer, photosensitive resin composition, pattern forming method, cured film, and electronic component 信越化学工业株式会社 2023-04-28 CN disclosed
EP-2949655-B1 REACTION CATALYST FOR CROSS COUPLING AND METHOD FOR MANUFACTURING AROMATIC COMPOUND HOKKO CHEM IND CO (JP) 2019-05-15 EP disclosed
US-9707551-B2 Reaction catalyst for cross-coupling and method for manufacturing aromatic compound HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) 2017-07-18 US disclosed
US-20150360214-A1 REACTION CATALYST FOR CROSS-COUPLING AND METHOD FOR MANUFACTURING AROMATIC COMPOUND HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) 2015-12-17 US disclosed
EP-2949655-A1 REACTION CATALYST FOR CROSS COUPLING AND METHOD FOR MANUFACTURING AROMATIC COMPOUND Hokko Chemical Industry Co., Ltd. (JP) 2015-12-02 EP disclosed
US-8058435-B2 Intermediate and process of preparation of ecteinascidin such as ecteinascidines-583,597 using such intermediate CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2011-11-15 US disclosed
US-20090171080-A1 Intermediate and Process of Preparation of Ecteinascidin Such as Ecteinascidines-583,597 Using Such Intermediate CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2009-07-02 US disclosed
US-6455720-B1 AS CATALYSTS TAKASAGO INTERNATIONAL CORPORATION (JP) 2002-09-24 US disclosed
US-20020058837-A1 2,2 (Diarlyl) Vinylphosphine compound, palladium catalyst thereof, and process for producing arylamine, diaryl, or arylalkyne with the catalyst TAKASAGO INTERNATIONAL CORPORATION (JP) 2002-05-16 US disclosed
US-6365776-B1 FROM ORGANOHALOGEN COMPOUND AND AMINE USING PALLADIUM COMPOUND CATALYST AND PROMOTER TAKASAGO INTERNATIONAL CORPORATION (JP) 2002-04-02 US disclosed
US-20020035295-A1 PROCESS FOR PRODUCING AROMATIC AMINES TAKASAGO INTERNATIONAL CORPORATION 2002-03-21 US disclosed
EP-1167372-A1 2,2-(Diaryl)vinylphosphine compound, palladium catalyst thereof, and process for producing arylamine, diaryl, or arylalkyne with the catalyst Takasago International Corporation (JP) 2002-01-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020035295-A1 PROCESS FOR PRODUCING AROMATIC AMINES TYR, DDC, PNMT MEN1 1606/4885KMT2A 359/4885ESR1 2983/4885
US-20020058837-A1 2,2 (Diarlyl) Vinylphosphine compound, palladium catalyst thereof, and process for producing arylamine, diaryl, or arylalkyne with the catalyst DDT, PDCD11, PLD2 MEN1 2881/4885KMT2A 170/4885ESR1 3506/4885
US-20260072035-A1 ENHANCED SPECIFICITY MASS TAG DNA ADDUCTOMICS DNMT3A, APEX1, CHAMP1 MEN1 2183/4885KMT2A 869/4885ESR1 132/4885
US-20090171080-A1 Intermediate and Process of Preparation of Ecteinascidin Such as Ecteinascidines-583,597 Using Such Intermediate MMP7, CCR7, AREG MEN1 688/4885KMT2A 4776/4885ESR1 1041/4885
US-20150360214-A1 REACTION CATALYST FOR CROSS-COUPLING AND METHOD FOR MANUFACTURING AROMATIC COMPOUND ALK, HRH4, HRH3 MEN1 3826/4885KMT2A 2197/4885ESR1 767/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.