Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | CCKBR | P32239 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ACLY | P53396 | 1/20 | 0.48 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.46 |
| ▸ | CCR2 | P41597 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7573141 | 0.92 | LMNA (0.49) | KMT2AMEN1GAAMAPTLMNA | |
| SCHEMBL12334073 | 0.82 | CCKBR (0.49) | KMT2AMEN1MAPTLMNARAB9A | |
| SCHEMBL7595111 | 0.79 | GAA (0.47) | KMT2AMEN1GAAMAPTLMNA | |
| SCHEMBL7591796 | 0.78 | CCR2 (0.46) | KMT2AMEN1GAAMAPTLMNA | |
| SCHEMBL12334053 | 0.75 | NR1H3 (0.54) | KMT2AMEN1MAPTLMNACCKBR | |
| SCHEMBL7592771 | 0.75 | MEN1 (0.74) | KMT2AMEN1GAALMNANPSR1 | |
| SCHEMBL4470291 | 0.74 | SLC40A1 (0.57) | KMT2AMEN1RAB9ACCKBRNPSR1 | |
| SCHEMBL12334668 | 0.74 | CCKBR (0.46) | KMT2AMEN1GAAMAPTLMNA | |
| SCHEMBL8013271 | 0.73 | CCKBR (0.49) | KMT2AMEN1MAPTCCKBRHTT | |
| SCHEMBL7572596 | 0.73 | MEN1 (0.67) | KMT2AMEN1GAAMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |