Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.49 |
| ▸ | CCR2 | P41597 | 2/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CCKBR | P32239 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | SLC20A2 | Q08357 | 1/20 | 0.44 |
| ▸ | SLC20A1 | Q8WUM9 | 1/20 | 0.44 |
| ▸ | CCR1 | P32246 | 1/20 | 0.44 |
| ▸ | CCR4 | P51679 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7572951 | 0.92 | KMT2A (0.54) | LMNARAB9AMAPTKMT2AMEN1 | |
| SCHEMBL12334073 | 0.77 | CCKBR (0.49) | LMNARAB9AMAPTKMT2AMEN1 | |
| SCHEMBL7591796 | 0.77 | CCR2 (0.46) | LMNAMAPTKMT2AMEN1NPSR1 | |
| SCHEMBL7595111 | 0.76 | GAA (0.47) | LMNAMAPTKMT2AMEN1NPSR1 | |
| SCHEMBL7572164 | 0.75 | CCR2 (0.59) | LMNAKMT2AMEN1NPSR1CCR2 | |
| SCHEMBL12334071 | 0.75 | RORA (0.47) | MAPTKMT2AMEN1NPSR1HTT | |
| SCHEMBL12221343 | 0.74 | CCR9 (0.66) | LMNAMAPTKMT2AMEN1HTT | |
| SCHEMBL3089394 | 0.74 | ACLY (0.62) | LMNARAB9AKMT2AMEN1HTT | |
| SCHEMBL7573862 | 0.72 | MCL1 (0.61) | LMNAKMT2AMEN1NPSR1CCR2 | |
| SCHEMBL7572611 | 0.72 | CCR2 (0.55) | LMNAKMT2AMEN1NPSR1CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |