Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CCR2 | P41597 | 1/20 | 0.46 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | ACLY | P53396 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CLK1 | P49759 | 1/20 | 0.41 |
| ▸ | CKS1B | P61024 | 1/20 | 0.41 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.41 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7591796 | 0.99 | CCR2 (0.46) | GAAMEN1KMT2ACCR2PTGES2 | |
| SCHEMBL7572951 | 0.79 | KMT2A (0.54) | GAAMEN1KMT2ACCR2ACLY | |
| SCHEMBL7573141 | 0.76 | LMNA (0.49) | GAAMEN1KMT2ACCR2LMNA | |
| SCHEMBL7592771 | 0.73 | MEN1 (0.74) | GAAMEN1KMT2ACCR2PTGES2 | |
| SCHEMBL7569677 | 0.73 | MEN1 (0.52) | GAAMEN1KMT2ACCR2PTGES2 | |
| SCHEMBL7572541 | 0.72 | FFAR1 (0.62) | GAAMEN1KMT2ACCR2LMNA | |
| SCHEMBL7572737 | 0.72 | MCL1 (0.60) | GAAMEN1KMT2ACCR2PTGES2 | |
| SCHEMBL3762909 | 0.70 | PGR (0.77) | GAAMEN1KMT2ANR3C1PGR | |
| SCHEMBL7577554 | 0.69 | MEN1 (0.55) | GAAMEN1KMT2ACCR2PTGES2 | |
| SCHEMBL7572596 | 0.69 | MEN1 (0.67) | GAAMEN1KMT2ACCR2PTGES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |