Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.63 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | RORC | P51449 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7588229 | 0.86 | PGR (0.53) | FFAR4HDAC1HDAC8SMN1; SMN2MAPT | |
| SCHEMBL7590053 | 0.84 | FFAR4 (0.59) | FFAR4HDAC1HDAC8SMN1; SMN2MAPT | |
| SCHEMBL1471295 | 0.83 | FFAR4 (0.54) | FFAR4HDAC1HDAC8SMN1; SMN2MAPT | |
| SCHEMBL7569815 | 0.81 | CYP19A1 (0.68) | FFAR4SMN1; SMN2MAPT | |
| SCHEMBL28913958 | 0.81 | KIF11 (0.69) | FFAR4HDAC1HDAC8SMN1; SMN2MAPT | |
| SCHEMBL26536689 | 0.81 | FFAR4 (0.63) | FFAR4HDAC1HDAC8SMN1; SMN2MAPT | |
| SCHEMBL26536700 | 0.81 | PKM (0.70) | FFAR4HDAC1HDAC8SMN1; SMN2MAPT | |
| SCHEMBL26537243 | 0.81 | SMN1; SMN2 (0.66) | FFAR4HDAC1HDAC8SMN1; SMN2MAPT | |
| SCHEMBL7570513 | 0.80 | FFAR4 (0.64) | FFAR4HDAC1HDAC8SMN1; SMN2MAPT | |
| SCHEMBL26536740 | 0.78 | FFAR4 (0.60) | FFAR4HDAC1HDAC8SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |