Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | PGR | P06401 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | PKLR | P30613 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | PLAU | P00749 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7569763 | 0.84 | FFAR4 (0.59) | FFAR4MAPTKMT2AKAT6AGAA | |
| SCHEMBL7572608 | 0.84 | KMT2A (0.61) | SMN1; SMN2LMNAFFAR4MAPTPGR | |
| SCHEMBL5598012 | 0.82 | PGR (0.72) | SMN1; SMN2LMNAFFAR4MAPTPGR | |
| SCHEMBL28913958 | 0.81 | KIF11 (0.69) | SMN1; SMN2FFAR4MAPTHDAC1HDAC8 | |
| SCHEMBL26536700 | 0.81 | PKM (0.70) | SMN1; SMN2FFAR4MAPTPKMPKLR | |
| SCHEMBL7573028 | 0.81 | FFAR4 (0.63) | SMN1; SMN2FFAR4MAPTHDAC1HDAC8 | |
| SCHEMBL26536689 | 0.81 | FFAR4 (0.63) | SMN1; SMN2FFAR4MAPTPGRHDAC1 | |
| SCHEMBL2614387 | 0.80 | SMN1; SMN2 (1.00) | SMN1; SMN2LMNAMAPTPGRPKM | |
| SCHEMBL7570513 | 0.80 | FFAR4 (0.64) | SMN1; SMN2FFAR4MAPTHDAC1HDAC8 | |
| SCHEMBL31681329 | 0.80 | FFAR4 (0.65) | SMN1; SMN2LMNAFFAR4MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230322715-A1 | BROAD SPECTRUM ANTI-CANCER COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230322715-A1 | BROAD SPECTRUM ANTI-CANCER COMPOUNDS | YTHDF1, YTHDF3, YTHDF2 | SMN1; SMN2 3408/4885LMNA 3852/4885FFAR4 2391/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.