Napropamide

Napropamide

SCHEMBL7578181

CCN(CC)C(=O)C(C)Oc1cccc2ccccc12.Nc1c([N+](=O)[O-])cnn1-c1c(Cl)cc(C(F)(F)F)cc1Cl

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.37
RAB9A P51151 1/20 0.35
PIN1 Q13526 1/20 0.35
GABRA2 P47869 6/20 0.34
GABRB2 P47870 6/20 0.34
GABRP O00591 5/20 0.34
GABRD O14764 5/20 0.34
GABRA1 P14867 5/20 0.34
GABRB1 P18505 5/20 0.34
GABRG2 P18507 5/20 0.34
GABRB3 P28472 5/20 0.34
GABRA5 P31644 5/20 0.34
GABRA3 P34903 5/20 0.34
GABRA4 P48169 5/20 0.34
GABRE P78334 5/20 0.34
GABRA6 Q16445 5/20 0.34
GABRG1 Q8N1C3 5/20 0.34
GABRG3 Q99928 5/20 0.34
GABRQ Q9UN88 5/20 0.34
LMNA P02545 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxyfluorfen SCHEMBL7582873 0.75 MEN1 (0.47) HPGDRAB9ALMNAMAPTNPSR1
Mecoprop SCHEMBL7581550 0.74 TSHR (0.48) GABRA2GABRB2GABRPGABRDGABRA1
SCHEMBL39558 0.74 ALDH1A1 (0.48) HPGDGABRA2GABRB2GABRPGABRD
SCHEMBL7579792 0.72 ALDH1A1 (0.37) RAB9AGABRA2GABRB2GABRPGABRD
Esprocarb SCHEMBL7586901 0.72 GABRA2 (0.36) GABRA2GABRB2GABRPGABRDGABRA1
Tebutam SCHEMBL7584123 0.72 TRPM8 (0.42) GABRA2GABRB2GABRPGABRDGABRA1
Prosulfocarb SCHEMBL7585925 0.72 GABRA2 (0.38) GABRA2GABRB2GABRPGABRDGABRA1
Napropamide SCHEMBL7584416 0.71 TDP1 (0.48) HPGDRAB9ALMNAMAPTNPSR1
Bispyribac SCHEMBL7583399 0.71 GABRP (0.41) GABRA2GABRB2GABRPGABRDGABRA1
Napropamide SCHEMBL2483381 0.71 TSHR (0.58) HPGDRAB9ALMNAMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT HPGD 687/4885RAB9A 1914/4885PIN1 23/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.