Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKBIA | P25963 | 2/20 | 0.55 |
| ▸ | RELA | Q04206 | 2/20 | 0.55 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.54 |
| ▸ | GUSB | P08236 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | ALPG | P10696 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.48 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.48 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | CRHBP | P24387 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7572486 | 0.87 | NFKBIA (0.56) | NFKBIARELANHERF1GUSBSMN1; SMN2 | |
| SCHEMBL15821362 | 0.82 | L3MBTL1 (0.55) | NFKBIARELANHERF1GUSBSMN1; SMN2 | |
| SCHEMBL10126623 | 0.78 | CA12 (0.59) | NHERF1SMN1; SMN2L3MBTL1MCL1MAPT | |
| SCHEMBL3470566 | 0.77 | SMN1; SMN2 (0.67) | NFKBIARELANHERF1GUSBSMN1; SMN2 | |
| SCHEMBL29335293 | 0.76 | NHERF1 (0.55) | NFKBIARELANHERF1GUSBSMN1; SMN2 | |
| SCHEMBL15821363 | 0.76 | CYP19A1 (0.57) | NFKBIARELANHERF1SMN1; SMN2L3MBTL1 | |
| SCHEMBL11415799 | 0.75 | NHERF1 (0.46) | NFKBIARELANHERF1GUSBSMN1; SMN2 | |
| SCHEMBL10661530 | 0.75 | CRHBP (0.71) | NHERF1SMN1; SMN2L3MBTL1MAPTMEN1 | |
| SCHEMBL2241186 | 0.74 | ALPL (0.60) | NFKBIARELANHERF1GUSBSMN1; SMN2 | |
| SCHEMBL5485573 | 0.74 | ALDH1A1 (0.62) | NHERF1SMN1; SMN2L3MBTL1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |