Flumioxazin

Flumioxazin

SCHEMBL7583354

C#CCN1C(=O)COc2cc(F)c(N3C(=O)C4=C(CCCC4)C3=O)cc21.C[C@@H](Oc1ccc(Oc2ncc(Cl)cc2F)cc1)C(=O)O.O=C(O)COc1ccc(Cl)c2cccnc12

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KMO O15229 2/20 0.33
PPARG P37231 3/20 0.33
PDE4A P27815 1/20 0.30
PDE4B Q07343 1/20 0.30
PDE4C Q08493 1/20 0.30
PDE4D Q08499 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Flumioxazin SCHEMBL7589028 0.89 LTA4H (0.33)
Flumioxazin SCHEMBL7581482 0.88 KMO (0.36) KMOPPARG
Flumioxazin SCHEMBL7581418 0.88 KMO (0.34) KMOPPARG
Flumioxazin SCHEMBL14655280 0.87 PKM (0.37) KMO
Flumipropyn SCHEMBL7589166 0.86 PPARG (0.35) PPARG
Clodinafop SCHEMBL7587910 0.83 KMO (0.30) KMO
Flumiciorac-Pentyl SCHEMBL7585717 0.81 L3MBTL1 (0.34) PPARG
Clodinafop SCHEMBL7578901 0.77 PPARG (0.36) PPARG
Clodinafop Propargyl SCHEMBL2372818 0.77 L3MBTL1 (0.45) PPARG
Flumioxazin SCHEMBL7588749 0.77 TP53 (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT KMO 318/4885PPARG 777/4885PDE4A 2817/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.