Flumipropyn

Flumipropyn

SCHEMBL7589166

C#CC(C)Oc1cc(N2C(=O)C3=C(CCCC3)C2=O)c(F)cc1Cl.C[C@@H](Oc1ccc(Oc2ncc(Cl)cc2F)cc1)C(=O)O.O=C(O)COc1ccc(Cl)c2cccnc12

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PPARG P37231 4/20 0.35
PKM P14618 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
MAPT P10636 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
LTA4H P09960 2/20 0.31
KCNH2 Q12809 1/20 0.31
P2RX3 P56373 1/20 0.30
PPOX P50336 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Flumipropyn SCHEMBL7580280 0.88 PPOX (0.37) L3MBTL1LTA4HKCNH2PPOX
Flumiciorac-Pentyl SCHEMBL7585717 0.88 L3MBTL1 (0.34) PPARGPKML3MBTL1MAPTSMN1; SMN2
Flumipropyn SCHEMBL7586408 0.87 TSHR (0.37) PPARGPKMPPOX
Flumipropyn SCHEMBL7587564 0.87 PKM (0.34) PPARGPKMMAPTSMN1; SMN2P2RX3
Flumioxazin SCHEMBL7583354 0.86 KMO (0.33) PPARG
Pentoxazone SCHEMBL7584420 0.81 PPARG (0.33) PPARGPKML3MBTL1MAPTSMN1; SMN2
Clodinafop SCHEMBL7578901 0.80 PPARG (0.36) PPARGPKML3MBTL1P2RX3
Clodinafop SCHEMBL7589232 0.79 DHODH (0.41)
Clodinafop Propargyl SCHEMBL2372818 0.79 L3MBTL1 (0.45) PPARGPKML3MBTL1MAPTSMN1; SMN2
Flumiciorac-Pentyl SCHEMBL7589562 0.77 L3MBTL1 (0.41) PKML3MBTL1LTA4HKCNH2PPOX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT PPARG 777/4885PKM 820/4885L3MBTL1 2160/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.