Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.47 |
| ▸ | OXTR | P30559 | 2/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.41 |
| ▸ | CLK1 | P49759 | 1/20 | 0.41 |
| ▸ | CLK2 | P49760 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.39 |
| ▸ | HTR3B | O95264 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.39 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7587322 | 0.87 | BCAT1 (0.48) | MAOBOXTRTRPM8NPC1TAS1R3 | |
| SCHEMBL6086523 | 0.87 | HTR3E (0.42) | MAOBNPC1TAS1R3TAS1R1RAB9A | |
| SCHEMBL7585802 | 0.78 | LMNA (0.51) | NPC1RAB9AKDM4ECA2 | |
| SCHEMBL7588083 | 0.78 | BCAT1 (0.45) | MAOBNPC1RAB9ABCAT1KDM4E | |
| SCHEMBL7588263 | 0.78 | POLB (0.53) | MAOBNPC1RAB9ACA2 | |
| SCHEMBL7586241 | 0.74 | HTR3E (0.40) | NPC1RAB9AHTR3EHTR3BHTR3A | |
| SCHEMBL5866855 | 0.72 | MAOB (0.60) | MAOBNPC1TAS1R3TAS1R1RAB9A | |
| SCHEMBL5866852 | 0.72 | MAOB (0.60) | MAOBNPC1TAS1R3TAS1R1RAB9A | |
| SCHEMBL5866857 | 0.70 | IDO1 (0.58) | MAOBTAS1R3TAS1R1BCAT1 | |
| SCHEMBL8311483 | 0.68 | TAS1R3 (0.60) | OXTRTAS1R3TAS1R1BCAT1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1246795-A2 | ANTIBACTERIAL AGENTS | Tularik Inc. (US) | 2002-10-09 | — | — | EP | disclosed |
| WO-2001051456-A2 | ANTIBACTERIAL AGENTS | TULARIK INC. (US) | 2001-07-19 | — | — | WO | disclosed |