Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 3/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.33 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.32 |
| ▸ | PDE7B | Q9NP56 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.31 |
| ▸ | HTR3B | O95264 | 1/20 | 0.31 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.31 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7588263 | 0.76 | POLB (0.53) | ALDH1A1NPC1MAPTRAB9ALMNA | |
| SCHEMBL5866885 | 0.75 | GPR35 (0.41) | GPR35ALDH1A1MAPTIDO1KDM4E | |
| SCHEMBL5866883 | 0.75 | GPR35 (0.41) | GPR35ALDH1A1MAPTIDO1KDM4E | |
| SCHEMBL5866888 | 0.73 | LMNA (0.52) | GPR35ALDH1A1LMNAIDO1CRHR1 | |
| SCHEMBL7586241 | 0.72 | HTR3E (0.40) | ALDH1A1NPC1MAPTRAB9AATM | |
| SCHEMBL6086523 | 0.70 | HTR3E (0.42) | GPR35ALDH1A1NPC1RAB9AATM | |
| SCHEMBL7585802 | 0.70 | LMNA (0.51) | ALDH1A1NPC1MAPTRAB9ALMNA | |
| SCHEMBL1983840 | 0.70 | GPR35 (0.68) | GPR35 | |
| SCHEMBL7582051 | 0.69 | GPR35 (0.41) | GPR35ALDH1A1LMNASMN1; SMN2HTR3E | |
| SCHEMBL6777820 | 0.68 | KEAP1 (0.40) | ALDH1A1MAPTLMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1246795-A2 | ANTIBACTERIAL AGENTS | Tularik Inc. (US) | 2002-10-09 | — | — | EP | disclosed |
| WO-2001051456-A2 | ANTIBACTERIAL AGENTS | TULARIK INC. (US) | 2001-07-19 | — | — | WO | disclosed |