Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 5/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | F12 | P00748 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7584637 | 0.88 | F12 (0.48) | POLBMEN1KMT2ANPC1RAB9A | |
| SCHEMBL6086523 | 0.85 | HTR3E (0.42) | KMT2ANPC1ALDH1A1RAB9AATM | |
| SCHEMBL7591071 | 0.78 | MAOB (0.47) | NPC1RAB9AMAOBCA2 | |
| SCHEMBL7588083 | 0.76 | BCAT1 (0.45) | MEN1KMT2ANPC1ALDH1A1RAB9A | |
| SCHEMBL7586299 | 0.76 | GPR35 (0.42) | MEN1KMT2ANPC1ALDH1A1RAB9A | |
| SCHEMBL5866846 | 0.73 | MEN1 (0.52) | POLBMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL5866847 | 0.73 | MEN1 (0.52) | POLBMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL7586241 | 0.72 | HTR3E (0.40) | MEN1KMT2ANPC1ALDH1A1RAB9A | |
| SCHEMBL5866850 | 0.71 | LMNA (0.62) | POLBMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL3609153 | 0.70 | POLB (0.59) | POLBMEN1KMT2ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1246795-A2 | ANTIBACTERIAL AGENTS | Tularik Inc. (US) | 2002-10-09 | — | — | EP | disclosed |
| WO-2001051456-A2 | ANTIBACTERIAL AGENTS | TULARIK INC. (US) | 2001-07-19 | — | — | WO | disclosed |