SCHEMBL1366779

SCHEMBL1366779

CO[C@H](C(=O)O)c1cccc(N)c1

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ CPN1 P15169 1/20 0.53
▸ CPB2 Q96IY4 1/20 0.53
▸ KYNU Q16719 1/20 0.43
▸ KDM4E B2RXH2 2/20 0.42
▸ ALDH1A1 P00352 4/20 0.42
▸ L3MBTL1 Q9Y468 1/20 0.42
▸ PBRM1 Q86U86 1/20 0.41
▸ KMT2A Q03164 1/20 0.40
▸ SMN1; SMN2 Q16637 1/20 0.40
▸ CYP3A4 P08684 1/20 0.40
▸ PPARA Q07869 1/20 0.39
▸ LMNA P02545 3/20 0.39
▸ HIF1A Q16665 1/20 0.39
▸ GAA P10253 1/20 0.39
▸ MAPK1 P28482 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30573232 1.00 CPN1 (0.53) CPN1CPB2KYNUKDM4EALDH1A1
SCHEMBL1104877 1.00 CPN1 (0.53) CPN1CPB2KYNUKDM4EALDH1A1
SCHEMBL1366777 1.00 CPN1 (0.53) CPN1CPB2KYNUKDM4EALDH1A1
SCHEMBL758770 0.82 CPN1 (0.53) CPN1CPB2KYNUALDH1A1L3MBTL1
SCHEMBL2190991 0.81 CPN1 (0.44) CPN1CPB2KDM4EALDH1A1L3MBTL1
SCHEMBL5038096 0.81 KYNU (0.55) KYNUKDM4EALDH1A1CYP3A4PPARA
SCHEMBL6611635 0.81 ACP3 (0.47) KDM4EL3MBTL1PPARALMNA
SCHEMBL14159225 0.79 ALDH1A1 (0.49) KDM4EALDH1A1L3MBTL1KMT2APPARA
SCHEMBL1145682 0.79 L3MBTL1 (0.56) L3MBTL1LMNA
SCHEMBL18890289 0.79 L3MBTL1 (0.56) L3MBTL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12291494-B2 Methods of treating fibrosis NOGRA PHARMA LIMITED (IE) 2025-05-06 — — US disclosed
US-20240279157-A1 METHODS OF TREATING FIBROSIS NOGRA PHARMA LIMITED (IE) 2024-08-22 — — US disclosed
US-11753365-B2 Methods of treating fibrosis NOGRA PHARMA LIMITED (IE) 2023-09-12 — — US disclosed
CN-116602950-A Methods of treating fibrosis 诺格拉制药有限公司 2023-08-18 — — CN disclosed
US-20220033346-A1 METHODS OF TREATING FIBROSIS NOGRA PHARMA LIMITED (IE) 2022-02-03 — — US disclosed
US-11046641-B2 Methods of treating fibrosis NOGRA PHARMA LIMITED (IE) 2021-06-29 — — US disclosed
US-20210113505-A1 METHODS OF TREATING HAIR RELATED CONDITIONS NOGRA PHARMA LTD (IE) 2021-04-22 — — US disclosed
EP-3628317-A1 METHODS OF TREATING FIBROSIS Nogra Pharma Limited (IE) 2020-04-01 — — EP disclosed
EP-2811993-B1 METHODS OF TREATING FIBROSIS NOGRA PHARMA LTD (IE) 2019-10-09 — — EP disclosed
EP-2895160-B1 METHODS OF TREATING HAIR RELATED CONDITIONS NOGRA PHARMA LTD (IE) 2018-05-30 — — EP disclosed
WO-2013156413-A1 METHODS OF TREATING LACTOSE INTOLERANCE NOGRA PHARMA LIMITED (IE) 2013-10-24 — — WO disclosed
WO-2013117744-A9 METHODS OF TREATING FIBROSIS NOGRA PHARMA LIMITED (IE) 2013-10-03 — — WO disclosed
WO-2013117744-A2 METHODS OF TREATING FIBROSIS NOGRA PHARMA LIMITED (IE) 2013-08-15 — — WO disclosed
US-8501806-B2 Methods for preventing or reducing colon carcinogenesis NOGRA PHARMA LIMITED (IE) 2013-08-06 — — US disclosed
US-20110288058-A1 Methods for Preventing or Reducing Colon Carcinogenesis NOGRA PHARMA LIMITED (IE) 2011-11-24 — — US disclosed
US-20110288177-A1 Methods for Preventing or Reducing Colon Carcinogenesis NOGRA PHARMA LIMITED (IE) 2011-11-24 — — US disclosed
US-20110152225-A1 PPAR-Gamma Agonists for the Induction of Cationic Antimicrobial Peptide Expression as Immunoprotective Stimulants NOGRA PHARMA LIMITED (IE) 2011-06-23 — — US disclosed
EP-2131829-A1 PPAR-GAMMA AGONISTS FOR THE INDUCTION OF CATIONIC ANTIMICROBIAL PEPTIDE EXPRESSION AS IMMUNOPROTECTIVE STIMULANTS Giuliani International Limited (IE) 2009-12-16 — — EP disclosed
WO-2008104557-A1 PPAR-GAMMA AGONISTS FOR THE INDUCTION OF CATIONIC ANTIMICROBIAL PEPTIDE EXPRESSION AS IMMUNOPROTECTIVE STIMULANTS GIULIANI INTERNATIONAL LIMITED (IE) 2008-09-04 — — WO disclosed
US-5707991-A TREATMENT OF NERVOUS SYSTEM DISORDERS, PARKINSON'S DISEASE RHONE-POULENC RORER S.A. (FR) 1998-01-13 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11753365-B2 Methods of treating fibrosis MMP1, MMP8, FABP2 CPN1 2301/4885CPB2 451/4885KYNU 3705/4885
US-20110288058-A1 Methods for Preventing or Reducing Colon Carcinogenesis NQO1, NFE2L2, CYBB CPN1 3258/4885CPB2 1102/4885KYNU 1817/4885
US-20210113505-A1 METHODS OF TREATING HAIR RELATED CONDITIONS EBP, AADAT, ALDH7A1 CPN1 2341/4885CPB2 2006/4885KYNU 274/4885
US-20240279157-A1 METHODS OF TREATING FIBROSIS MMP1, MMP8, FABP2 CPN1 2301/4885CPB2 451/4885KYNU 3705/4885
US-20110288177-A1 Methods for Preventing or Reducing Colon Carcinogenesis APC, GSTK1, GSTA1 CPN1 3029/4885CPB2 1741/4885KYNU 3063/4885
US-12291494-B2 Methods of treating fibrosis MMP1, MMP8, FABP2 CPN1 2301/4885CPB2 451/4885KYNU 3705/4885
US-11046641-B2 Methods of treating fibrosis MMP1, MMP8, FABP2 CPN1 2301/4885CPB2 451/4885KYNU 3705/4885
US-20110152225-A1 PPAR-Gamma Agonists for the Induction of Cationic Antimicrobial Peptide Expression as Immunoprotective Stimulants PPARG, FABP2, PPARD CPN1 2091/4885CPB2 1744/4885KYNU 3961/4885
US-20220033346-A1 METHODS OF TREATING FIBROSIS MMP1, MMP8, FABP2 CPN1 2301/4885CPB2 451/4885KYNU 3705/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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