Pentoxazone

Pentoxazone

SCHEMBL7584420

CC(C)=C1OC(=O)N(c2cc(OC3CCCC3)c(Cl)cc2F)C1=O.C[C@@H](Oc1ccc(Oc2ncc(Cl)cc2F)cc1)C(=O)O.O=C(O)COc1ccc(Cl)c2cccnc12

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PPARG P37231 3/20 0.33
L3MBTL1 Q9Y468 2/20 0.32
PPOX P50336 2/20 0.31
PDE4D Q08499 1/20 0.31
MAPT P10636 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
PKM P14618 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pentoxazone SCHEMBL7583345 0.89 PPOX (0.37) L3MBTL1PPOX
Pentoxazone SCHEMBL7578499 0.89 PPOX (0.36) PPARGL3MBTL1PPOXPDE4DSMN1; SMN2
Pentoxazone SCHEMBL7579877 0.88 PPOX (0.34) PPARGL3MBTL1PPOXPDE4DMAPT
Pentoxazone SCHEMBL7934081 0.88 PKM (0.39) L3MBTL1PPOXPDE4DMAPTSMN1; SMN2
Flumipropyn SCHEMBL7589166 0.81 PPARG (0.35) PPARGL3MBTL1PPOXMAPTSMN1; SMN2
Flumiciorac-Pentyl SCHEMBL7585717 0.79 L3MBTL1 (0.34) PPARGL3MBTL1PPOXMAPTSMN1; SMN2
Pentoxazone SCHEMBL7587243 0.77 TP53 (0.42) PPOXMAPTSMN1; SMN2
Pentoxazone SCHEMBL7577616 0.77 LIPE (0.36) PPOXSMN1; SMN2
Flumioxazin SCHEMBL7583354 0.76 KMO (0.33) PPARGPDE4D
Pentoxazone SCHEMBL7582107 0.76 SLC6A9 (0.36) PPOX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT PPARG 777/4885L3MBTL1 2160/4885PPOX 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.