SCHEMBL7592823

SCHEMBL7592823

CC(C)CCOC(=O)c1cc(C(F)(F)F)c(F)c(F)c1F

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.42
PKM P14618 2/20 0.42
KMT2A Q03164 2/20 0.42
KDM4E B2RXH2 1/20 0.42
GAA P10253 1/20 0.42
GABRA1 P14867 1/20 0.39
GABRB1 P18505 1/20 0.39
GABRA3 P34903 1/20 0.39
GABRB2 P47870 1/20 0.39
MAPK1 P28482 1/20 0.38
HSD17B10 Q99714 1/20 0.38
CYP19A1 P11511 1/20 0.34
TSHR P16473 1/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
EGFR P00533 2/20 0.32
SCN8A Q9UQD0 1/20 0.32
SCN10A Q9Y5Y9 1/20 0.32
CTSS P25774 1/20 0.32
PPARG P37231 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7595676 0.86 ALDH1A1 (0.49) ALDH1A1KMT2AKDM4EGAAMAPK1
SCHEMBL7591337 0.84 ALDH1A1 (0.47) ALDH1A1KDM4EMAPK1HSD17B10TSHR
SCHEMBL7590153 0.82 TSHR (0.50) ALDH1A1MAPK1HSD17B10TSHRL3MBTL1
SCHEMBL7593446 0.81 TSHR (0.44) ALDH1A1KDM4ETSHRL3MBTL1TDP1
SCHEMBL7595389 0.81 TSHR (0.51) ALDH1A1KDM4EMAPK1HSD17B10TSHR
SCHEMBL7597693 0.78 CA12 (0.41) ALDH1A1PKMKDM4EHSD17B10
SCHEMBL7590145 0.77 L3MBTL1 (0.39) ALDH1A1PKMGABRA1GABRA3L3MBTL1
SCHEMBL7595315 0.77 ALDH1A1 (0.39) ALDH1A1L3MBTL1CTSS
SCHEMBL7595297 0.76 CFTR (0.50) KDM4E
SCHEMBL20695629 0.75 ALDH1A1 (0.56) ALDH1A1PKMKMT2AKDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0968994-B1 PROCESS FOR PRODUCING SUBSTITUTED TRIFLUOROBENZOIC ACIDS AND ESTERS THEREOF UBE INDUSTRIES (JP) 2002-11-06 EP claimed