SCHEMBL7597693

SCHEMBL7597693

CC(C)OC(=O)c1cc(C(F)(F)F)c(F)c(F)c1F

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 6/20 0.41
CA1 P00915 6/20 0.41
CA2 P00918 6/20 0.41
CA7 P43166 6/20 0.41
CA9 Q16790 6/20 0.41
CA14 Q9ULX7 6/20 0.41
PDK2 Q15119 1/20 0.37
KDM4E B2RXH2 4/20 0.35
ALDH1A1 P00352 4/20 0.35
HPGD P15428 2/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
HSD17B10 Q99714 1/20 0.35
NPC1 O15118 1/20 0.35
CES2 O00748 1/20 0.34
CFTR P13569 1/20 0.34
MAPT P10636 1/20 0.34
PKM P14618 1/20 0.34
THRB P10828 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7590145 0.86 L3MBTL1 (0.39) ALDH1A1CES2CFTRPKM
SCHEMBL7595315 0.83 ALDH1A1 (0.39) ALDH1A1CFTR
SCHEMBL7595297 0.81 CFTR (0.50) CA12CA1CA2CA7CA9
SCHEMBL7595676 0.80 ALDH1A1 (0.49) KDM4EALDH1A1NPC1MAPT
SCHEMBL7591648 0.79 AR (0.37) CES2CFTRSOS1
SCHEMBL7592823 0.78 ALDH1A1 (0.42) KDM4EALDH1A1HSD17B10PKM
SCHEMBL7593446 0.77 TSHR (0.44) CA12CA1CA2CA7CA9
SCHEMBL16628377 0.76 CA12 (0.47) CA12CA1CA2CA7CA9
SCHEMBL7591337 0.75 ALDH1A1 (0.47) PDK2KDM4EALDH1A1HSD17B10
SCHEMBL20332068 0.74 MAPT (0.49) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0968994-B1 PROCESS FOR PRODUCING SUBSTITUTED TRIFLUOROBENZOIC ACIDS AND ESTERS THEREOF UBE INDUSTRIES (JP) 2002-11-06 EP claimed