SCHEMBL7595676

SCHEMBL7595676

CC(C)COC(=O)c1cc(C(F)(F)F)c(F)c(F)c1F

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.49
TSHR P16473 1/20 0.49
CACNA1F O60840 3/20 0.40
CACNA1D Q01668 3/20 0.40
CACNA1S Q13698 3/20 0.40
CACNA1C Q13936 3/20 0.40
KDM4E B2RXH2 1/20 0.39
MAPT P10636 3/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
NPC1 O15118 1/20 0.36
HTT P42858 1/20 0.36
RAB9A P51151 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
MEN1 O00255 1/20 0.36
TP53 P04637 1/20 0.36
NPY1R P25929 1/20 0.36
NPY2R P49146 1/20 0.36
KMT2A Q03164 1/20 0.36
ATM Q13315 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7592823 0.86 ALDH1A1 (0.42) ALDH1A1TSHRKDM4EHTTTDP1
SCHEMBL7593446 0.83 TSHR (0.44) ALDH1A1TSHRKDM4EMAPTHTT
SCHEMBL19795501 0.83 ALDH1A1 (0.56) ALDH1A1TSHRCACNA1FCACNA1DCACNA1S
SCHEMBL7591337 0.81 ALDH1A1 (0.47) ALDH1A1TSHRKDM4ETDP1TP53
SCHEMBL7597693 0.80 CA12 (0.41) ALDH1A1KDM4EMAPTNPC1
SCHEMBL7590145 0.79 L3MBTL1 (0.39) ALDH1A1SMN1; SMN2TP53CTSS
SCHEMBL7590153 0.78 TSHR (0.50) ALDH1A1TSHRTDP1TP53MAPK1
SCHEMBL7595297 0.78 CFTR (0.50) KDM4EMAPT
SCHEMBL7595389 0.77 TSHR (0.51) ALDH1A1TSHRKDM4ETDP1TP53
SCHEMBL7595315 0.76 ALDH1A1 (0.39) ALDH1A1CTSS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0968994-B1 PROCESS FOR PRODUCING SUBSTITUTED TRIFLUOROBENZOIC ACIDS AND ESTERS THEREOF UBE INDUSTRIES (JP) 2002-11-06 EP claimed