Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 6/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1334167 | 0.87 | PLA2G2A (0.35) | HIF1AMAPTL3MBTL1RAB9AKDM4E | |
| SCHEMBL8816487 | 0.85 | ALDH1A1 (0.38) | HIF1AMAPTPOLBKDM4EALDH1A1 | |
| SCHEMBL7599240 | 0.80 | SMN1; SMN2 (0.37) | MAPTRAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL1333813 | 0.80 | HIF1A (0.34) | HIF1AMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL1388942 | 0.74 | ALDH1A1 (0.39) | HIF1ATSHRMAPTL3MBTL1KDM4E | |
| SCHEMBL5646001 | 0.73 | MAPT (0.36) | HIF1AMAPTPOLBKDM4EALDH1A1 | |
| SCHEMBL1331927 | 0.71 | KDM4E (0.33) | HIF1ATSHRL3MBTL1POLBKDM4E | |
| SCHEMBL7131287 | 0.70 | KDM4E (0.40) | TSHRMAPTL3MBTL1POLBKDM4E | |
| SCHEMBL5650291 | 0.70 | RAB9A (0.39) | HIF1AMAPTPOLBRAB9AKDM4E | |
| SCHEMBL5648658 | 0.70 | HIF1A (0.33) | HIF1ATSHRMAPTL3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112264-B1 | POLYALKOXYLATED NAPHTHOPYRANS | TRANSITIONS OPTICAL INC (US) | 2002-11-27 | — | — | EP | claimed |
| US-5961892-A | PHOTOCHROMIC | PPG INDUSTRIES OHIO, INC. (US) | 1999-10-05 | — | — | US | claimed |
| EP-1112264-B1 | POLYALKOXYLATED NAPHTHOPYRANS | TRANSITIONS OPTICAL INC (US) | 2002-11-27 | — | — | EP | disclosed |