Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7596283 | 0.84 | HDAC1 (0.32) | HDAC1HDAC2CHRM1AKR1A1CHRM3 | |
| SCHEMBL14813255 | 0.82 | TAS1R3 (0.33) | HDAC1HDAC2CHRM1AKR1A1CHRM3 | |
| SCHEMBL585431 | 0.79 | POLB (0.33) | HDAC1HDAC2TDP1ALDH1A1HDAC3 | |
| SCHEMBL585432 | 0.79 | POLB (0.33) | HDAC1HDAC2TDP1ALDH1A1HDAC3 | |
| SCHEMBL584054 | 0.78 | CTSK (0.33) | — | |
| SCHEMBL14813217 | 0.77 | CHRM1 (0.41) | HDAC1HDAC2CHRM1AKR1A1CHRM3 | |
| SCHEMBL5514967 | 0.71 | HDAC1 (0.70) | HDAC1HDAC2CHRM1AKR1A1CHRM3 | |
| SCHEMBL7587948 | 0.67 | ALDH1A1 (0.41) | HDAC1HDAC2CHRM1AKR1A1CHRM3 | |
| SCHEMBL112653 | 0.67 | ALDH1A1 (0.47) | HDAC1HDAC2CHRM1AKR1A1CHRM3 | |
| SCHEMBL593846 | 0.66 | FFAR3 (0.33) | HDAC1HDAC2CHRM1AKR1A1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8765204-B2 | Carbonothioates as flavours and fragrances | GIVAUDAN S.A. (CH) | 2014-07-01 | — | — | US | claimed |
| EP-2417105-B1 | CARBONOTHIOATES AS FLAVOURS AND FRAGRANCES | GIVAUDAN SA (CH) | 2013-04-03 | — | — | EP | claimed |
| US-20120052178-A1 | Carbonothioates As Flavours and Fragrances | GIVAUDAN SA (CH) | 2012-03-01 | — | — | US | claimed |
| EP-2417105-A1 | CARBONOTHIOATES AS FLAVOURS AND FRAGRANCES | Givaudan SA (CH) | 2012-02-15 | — | — | EP | claimed |
| WO-2010115920-A1 | CARBONOTHIOATES AS FLAVOURS AND FRAGRANCES | GIVAUDAN SA (CH) | 2010-10-14 | — | — | WO | claimed |
| US-11758933-B2 | High intensity sweeteners | FIRMENICH INCORPORATED (US) | 2023-09-19 | — | — | US | disclosed |
| US-11357246-B2 | High intensity sweeteners | FIRMENICH INCORPORATED (US) | 2022-06-14 | — | — | US | disclosed |
| US-20210227863-A1 | HIGH INTENSITY SWEETENERS | SENOMYX, INC. | 2021-07-29 | — | — | US | disclosed |
| US-8765204-B2 | Carbonothioates as flavours and fragrances | GIVAUDAN S.A. (CH) | 2014-07-01 | — | — | US | disclosed |
| EP-2417105-B1 | CARBONOTHIOATES AS FLAVOURS AND FRAGRANCES | GIVAUDAN SA (CH) | 2013-04-03 | — | — | EP | disclosed |
| US-20120052178-A1 | Carbonothioates As Flavours and Fragrances | GIVAUDAN SA (CH) | 2012-03-01 | — | — | US | disclosed |
| EP-2417105-A1 | CARBONOTHIOATES AS FLAVOURS AND FRAGRANCES | Givaudan SA (CH) | 2012-02-15 | — | — | EP | disclosed |
| WO-2010115920-A1 | CARBONOTHIOATES AS FLAVOURS AND FRAGRANCES | GIVAUDAN SA (CH) | 2010-10-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120052178-A1 | Carbonothioates As Flavours and Fragrances | PFAS, MGMT, RNGTT | HDAC1 2218/4885HDAC2 2637/4885CHRM1 4488/4885 |
| US-11357246-B2 | High intensity sweeteners | TAS2R40, TAS2R60, TAS1R1 | HDAC1 215/4885HDAC2 879/4885CHRM1 3064/4885 |
| US-20210227863-A1 | HIGH INTENSITY SWEETENERS | TAS2R40, TAS2R60, TAS1R1 | HDAC1 215/4885HDAC2 879/4885CHRM1 3064/4885 |
| US-11758933-B2 | High intensity sweeteners | TAS2R40, TAS2R60, TAS1R1 | HDAC1 215/4885HDAC2 879/4885CHRM1 3064/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.