SCHEMBL759712

SCHEMBL759712

CC(C)(C)OC(=O)NNC(=O)CN

nearest known ligand 0.56

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
APLNR P35414 1/20 0.56
GAA P10253 4/20 0.40
KMT2A Q03164 4/20 0.40
MEN1 O00255 3/20 0.40
MAPK1 P28482 1/20 0.40
TDP1 Q9NUW8 1/20 0.39
CA1 P00915 3/20 0.38
CA2 P00918 3/20 0.38
CA7 P43166 2/20 0.38
MAOA P21397 1/20 0.38
MAOB P27338 1/20 0.38
LMNA P02545 1/20 0.36
POLB P06746 1/20 0.36
CA12 O43570 3/20 0.36
CA14 Q9ULX7 2/20 0.36
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
CA9 Q16790 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10087239 0.84 APLNR (0.53) APLNRGAAKMT2AMEN1MAPK1
SCHEMBL284141 0.82 APLNR (0.55) APLNRGAAKMT2AMEN1MAPK1
SCHEMBL22018439 0.81 TDP1 (0.44) APLNRGAAKMT2AMEN1TDP1
SCHEMBL16906258 0.81 APLNR (0.58) APLNRGAAKMT2AMEN1MAPK1
SCHEMBL18476417 0.79 APLNR (0.56) APLNRGAAKMT2AMEN1MAPK1
SCHEMBL4424589 0.78 APLNR (0.47) APLNRGAAKMT2AMEN1MAPK1
SCHEMBL8842138 0.78 APLNR (0.47) APLNRGAAKMT2AMEN1MAPK1
SCHEMBL19273270 0.78 APLNR (0.48) APLNRGAAKMT2AMEN1MAPK1
SCHEMBL7052487 0.78 APLNR (0.54) APLNRGAAKMT2AMEN1MAPK1
SCHEMBL3458796 0.78 APLNR (0.54) APLNRGAAKMT2AMEN1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12497460-B2 Anti-MSR1 antibodies and methods of use thereof REGENERON PHARMACEUTICALS, INC. (US) 2025-12-16 US disclosed
US-20250064954-A1 STEROIDS AND ANTIBODY-CONJUGATES THEREOF REGENERON PHARMACEUTICALS, INC. 2025-02-27 US disclosed
CN-118955604-A Steroid compounds and antibody conjugates thereof 里珍纳龙药品有限公司 2024-11-15 CN disclosed
US-20240342299-A1 STEROIDS AND ANTIBODY-CONJUGATES THEREOF REGENERON PHARMA (US) 2024-10-17 US disclosed
US-12070506-B2 Steroids and antibody-conjugates thereof REGENERON PHARMACEUTICALS, INC. (US) 2024-08-27 US disclosed
CN-112004557-B Steroid compounds and antibody conjugates thereof 里珍纳龙药品有限公司 2024-07-30 CN disclosed
US-20230277677-A1 POLYMERIC CONJUGATES AND USES THEREOF RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2023-09-07 US disclosed
US-11666656-B2 Polymeric conjugates and uses thereof RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2023-06-06 US disclosed
US-20230079407-A1 ANTI-MSR1 ANTIBODIES AND METHODS OF USE THEREOF REGENERON PHARMACEUTICALS, INC. 2023-03-16 US disclosed
US-11377502-B2 Anti-MSR1 antibodies and methods of use thereof REGENERON PHARMACEUTICALS, INC. (US) 2022-07-05 US disclosed
US-20190209702-A1 STEROIDS AND ANTIBODY-CONJUGATES THEREOF REGENERON PHARMACEUTICALS, INC. 2019-07-11 US disclosed
WO-2019136487-A2 STEROIDS AND ANTIBODY-CONJUGATES THEREOF REGENERON PHARMACEUTICALS, INC. (US) 2019-07-11 WO disclosed
WO-2017145164-A9 POLYMERIC CONJUGATES AND USES THEREOF RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2018-07-26 WO disclosed
US-20180030207-A1 LINEAR CYCLODEXTRIN COPOLYMERS CALIFORNIA INSTITUTE OF TECHNOLOGY 2018-02-01 US disclosed
WO-2017145164-A1 POLYMERIC CONJUGATES AND USES THEREOF RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2017-08-31 WO disclosed
US-20150203634-A1 LINEAR CYCLODEXTRIN COPOLYMERS CALIFORNIA INSTITUTE OF TECHNOLOGY 2015-07-23 US disclosed
US-20120053165-A1 Novel Phenyl Imidazoles and Phenyl Triazoles As Gamma-Secretase Modulators PFIZER INC. (US) 2012-03-01 US disclosed
US-20120053165-A1 Novel Phenyl Imidazoles and Phenyl Triazoles As Gamma-Secretase Modulators PFIZER INC. (US) 2012-03-01 US disclosed
WO-2010100606-A1 NOVEL PHENYL IMIDAZOLES AND PHENYL TRIAZOLES AS GAMMA-SECRETASE MODULATORS PFIZER INC. (US) 2010-09-10 WO disclosed
US-RE41252-E1 Peptidyl prodrugs and linkers and stabilizers useful therefor MEDAREX, INC. (US) 2010-04-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190209702-A1 STEROIDS AND ANTIBODY-CONJUGATES THEREOF SERPINA6, NR3C1, NR3C2 APLNR 1967/4885GAA 2471/4885KMT2A 4385/4885
US-20240342299-A1 STEROIDS AND ANTIBODY-CONJUGATES THEREOF SERPINA6, NR3C1, NR3C2 APLNR 1967/4885GAA 2471/4885KMT2A 4385/4885
US-12070506-B2 Steroids and antibody-conjugates thereof SERPINA6, NR3C1, NR3C2 APLNR 1967/4885GAA 2471/4885KMT2A 4385/4885
US-20120053165-A1 Novel Phenyl Imidazoles and Phenyl Triazoles As Gamma-Secretase Modulators BACE1, BACE2, PSEN1 APLNR 2878/4885GAA 12/4885KMT2A 3246/4885
US-20180030207-A1 LINEAR CYCLODEXTRIN COPOLYMERS DDOST, SI, PDIA6 APLNR 4650/4885GAA 34/4885KMT2A 4873/4885
US-11666656-B2 Polymeric conjugates and uses thereof CD44, DCLRE1A, CD74 APLNR 38/4885GAA 1090/4885KMT2A 1781/4885
US-20230079407-A1 ANTI-MSR1 ANTIBODIES AND METHODS OF USE THEREOF CD47, MSR1, LDLR APLNR 59/4885GAA 2281/4885KMT2A 710/4885
US-20230277677-A1 POLYMERIC CONJUGATES AND USES THEREOF CD44, DCLRE1A, CD74 APLNR 38/4885GAA 1090/4885KMT2A 1781/4885
US-20250064954-A1 STEROIDS AND ANTIBODY-CONJUGATES THEREOF SERPINA6, NR3C1, NR3C2 APLNR 1967/4885GAA 2471/4885KMT2A 4385/4885
US-12497460-B2 Anti-MSR1 antibodies and methods of use thereof CD47, MSR1, LDLR APLNR 59/4885GAA 2281/4885KMT2A 710/4885
US-11377502-B2 Anti-MSR1 antibodies and methods of use thereof CD47, MSR1, LDLR APLNR 59/4885GAA 2281/4885KMT2A 710/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.