Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 10/20 | 0.71 |
| ▸ | PGR | P06401 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | APP | P05067 | 1/20 | 0.51 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.51 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1443643 | 0.87 | CCR2 (0.62) | CCR2PGRLMNAAPPHSD17B2 | |
| SCHEMBL9933533 | 0.85 | CCR2 (0.81) | CCR2PGRHSD17B2 | |
| SCHEMBL5956021 | 0.84 | APP (0.66) | CCR2LMNAAPP | |
| SCHEMBL9935049 | 0.83 | CCR2 (0.62) | CCR2PGRLMNAHSD17B2 | |
| SCHEMBL7590023 | 0.83 | CCR2 (0.51) | CCR2LMNA | |
| SCHEMBL7596280 | 0.82 | CCR2 (0.56) | CCR2PGRLMNA | |
| SCHEMBL7588944 | 0.82 | ALDH1A1 (0.56) | CCR2LMNA | |
| SCHEMBL27943891 | 0.81 | CCR2 (0.59) | CCR2PGRLMNAHSD17B2 | |
| SCHEMBL15009279 | 0.81 | MAPT (0.51) | CCR2PGRLMNA | |
| SCHEMBL7573875 | 0.81 | KEAP1 (0.55) | CCR2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |