Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | GAA | P10253 | 6/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.49 |
| ▸ | BRD1 | O95696 | 1/20 | 0.49 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CASP6 | P55212 | 1/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7591229 | 0.84 | CA12 (0.50) | ALDH1A1GAALMNAMAPTSMN1; SMN2 | |
| SCHEMBL23555160 | 0.83 | ALDH1A1 (0.71) | ALDH1A1GAALMNAMAPTPKM | |
| SCHEMBL7571609 | 0.83 | MAPT (0.54) | CCR2ALDH1A1GAALMNAMAPT | |
| SCHEMBL7588944 | 0.82 | ALDH1A1 (0.56) | CCR2ALDH1A1GAALMNAMAPT | |
| SCHEMBL7597807 | 0.82 | CCR2 (0.71) | CCR2LMNAPGR | |
| SCHEMBL7573977 | 0.82 | PKM (0.64) | ALDH1A1GAALMNAMAPTSMN1; SMN2 | |
| SCHEMBL7595414 | 0.82 | ALDH1A1 (0.70) | ALDH1A1GAALMNAMAPTGFER | |
| SCHEMBL7590023 | 0.81 | CCR2 (0.51) | CCR2ALDH1A1GAALMNAMAPT | |
| SCHEMBL7589428 | 0.79 | FFAR4 (0.67) | ALDH1A1LMNAMAPTTP53MEN1 | |
| SCHEMBL7573875 | 0.79 | KEAP1 (0.55) | CCR2ALDH1A1GAALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |