Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.43 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26192643 | 1.00 | ALDH1A1 (0.50) | ALDH1A1TSHRTHRBMEN1KMT2A | |
| SCHEMBL8024528 | 1.00 | ALDH1A1 (0.50) | ALDH1A1TSHRTHRBMEN1KMT2A | |
| SCHEMBL20078294 | 1.00 | ALDH1A1 (0.50) | ALDH1A1TSHRTHRBMEN1KMT2A | |
| SCHEMBL862847 | 0.96 | — | — | |
| SCHEMBL19309079 | 0.91 | MEN1 (0.56) | ALDH1A1TSHRMEN1KMT2AMAPK1 | |
| SCHEMBL5155263 | 0.91 | MEN1 (0.56) | ALDH1A1TSHRMEN1KMT2AMAPK1 | |
| SCHEMBL12893042 | 0.89 | SMN1; SMN2 (0.41) | ALDH1A1TSHRTHRBMEN1KMT2A | |
| SCHEMBL14924288 | 0.89 | SMN1; SMN2 (0.41) | ALDH1A1TSHRTHRBMEN1KMT2A | |
| SCHEMBL13113468 | 0.89 | ALDH1A1 (0.41) | ALDH1A1TSHRTHRBMEN1KMT2A | |
| SCHEMBL5157716 | 0.89 | MAPK1 (0.55) | ALDH1A1TSHRMEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240252488-A1 | MLKL BINDING OR DEGRADING COMPOUND AND PHARMACEUTICAL USE THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2024-08-01 | — | — | US | claimed |
| WO-2025082283-A1 | LIGAND COMPOUND OF CYCLOPEPTIDE STRUCTURE, NUCLIDE MARKER THEREOF, PHARMACEUTICAL COMPOSITION, AND USE | 四川科伦博泰生物医药股份有限公司 | 2025-04-24 | — | — | WO | disclosed |
| US-20240252488-A1 | MLKL BINDING OR DEGRADING COMPOUND AND PHARMACEUTICAL USE THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2024-08-01 | — | — | US | disclosed |
| WO-2023102747-A1 | ANTIMALARIAL AGENTS | MERCK SHARP & DOHME LLC (US) | 2023-06-15 | — | — | WO | disclosed |
| WO-2023107356-A1 | ANTIMALARIAL AGENTS | MERCK SHARP & DOHME LLC (US) | 2023-06-15 | — | — | WO | disclosed |
| WO-2021027502-A1 | ANTIMALARIAL AGENTS | MERCK SHARP & DOHME CORP. (US) | 2021-02-18 | — | — | WO | disclosed |
| US-20170128456-A1 | CARBON MONOXIDE-RELEASING MOLECULES FOR THERAPEUTIC APPLICATIONS AND METHODS OF MAKING AND USING THEREOF | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC, (US) | 2017-05-11 | — | — | US | disclosed |
| US-20160102104-A1 | Ataxia Telengiectasia And Rad3-Related (ATR) Protein Kinase Inhibitors | Atrin Pharmaceuticals LLC (US) | 2016-04-14 | — | — | US | disclosed |
| US-8138361-B2 | C-10 carbamates of taxanes | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2012-03-20 | — | — | US | disclosed |
| US-8138361-B2 | C-10 carbamates of taxanes | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2012-03-20 | — | — | US | disclosed |
| US-20090306014-A1 | C-10 CARBAMATES OF TAXANES | ACIDOPHIL LLC (US) | 2009-12-10 | — | — | US | disclosed |
| US-20090306014-A1 | C-10 CARBAMATES OF TAXANES | ACIDOPHIL LLC (US) | 2009-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240252488-A1 | MLKL BINDING OR DEGRADING COMPOUND AND PHARMACEUTICAL USE THEREOF | MLKL, PCSK9, CTSA | ALDH1A1 3601/4885TSHR 4534/4885THRB 3911/4885 |
| US-20170128456-A1 | CARBON MONOXIDE-RELEASING MOLECULES FOR THERAPEUTIC APPLICATIONS AND METHODS OF MAKING AND USING THEREOF | MB, CYC1, COX15 | ALDH1A1 800/4885TSHR 2656/4885THRB 3010/4885 |
| US-20160102104-A1 | Ataxia Telengiectasia And Rad3-Related (ATR) Protein Kinase Inhibitors | ATR, CHEK1, CHEK2 | ALDH1A1 4356/4885TSHR 986/4885THRB 509/4885 |
| US-20090306014-A1 | C-10 CARBAMATES OF TAXANES | CASP10, S100A10, ATXN10 | ALDH1A1 1408/4885TSHR 3572/4885THRB 2579/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.