Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR88 | Q9GZN0 | 9/20 | 0.46 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 6/20 | 0.39 |
| ▸ | ACACA | Q13085 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7596318 | 0.87 | GPR88 (0.44) | GPR88ACACBACACA | |
| SCHEMBL7598437 | 0.86 | ALOX5 (0.55) | ACACBALOX5 | |
| SCHEMBL7597931 | 0.86 | ALDH1A1 (0.44) | ALOX5 | |
| SCHEMBL7595296 | 0.86 | ALDH1A1 (0.44) | ALOX5 | |
| Hydrochloric Acid SCHEMBL7600447 | 0.86 | ALOX5 (0.42) | ALOX5 | |
| SCHEMBL7600674 | 0.85 | TRPM8 (0.46) | ALOX5 | |
| Hydrochloric Acid SCHEMBL7600168 | 0.85 | ALDH1A1 (0.46) | ALOX5 | |
| Hydrochloric Acid SCHEMBL7594995 | 0.84 | TRPM8 (0.45) | ALOX5 | |
| SCHEMBL7597577 | 0.84 | CTSS (0.46) | GPR88ACACAALOX5 | |
| SCHEMBL7596331 | 0.82 | TRPM8 (0.41) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017672-B1 | NEW NPY ANTAGONISTS | ASTRAZENECA AB (SE) | 2002-11-27 | — | — | EP | disclosed |
| EP-1017672-A1 | NEW NPY ANTAGONISTS | AstraZeneca AB (SE) | 2000-07-12 | — | — | EP | disclosed |
| WO-1999015498-A1 | NEW NPY ANTAGONISTS | ASTRAZENECA AB (SE) | 1999-04-01 | — | — | WO | disclosed |