Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27670358 | 0.86 | GABRA1 (0.31) | CA2GABRA1GABRB2ALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL28408729 | 0.79 | CA2 (0.35) | CA2GABRA1GABRB2ALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL4946925 | 0.78 | CYP1A2 (0.31) | CA2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL29612285 | 0.78 | CA2 (0.34) | CA2GABRA1GABRB2 | |
| SCHEMBL30108371 | 0.77 | CA2 (0.36) | CA2GABRA1GABRB2ALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL5616373 | 0.77 | ALDH1A1 (0.32) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL16829539 | 0.75 | PTGS2 (0.34) | — | |
| Hydrochloric Acid SCHEMBL7203230 | 0.75 | KIF11 (0.34) | ALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL29612278 | 0.75 | KIF11 (0.34) | ALDH1A1TSHR | |
| SCHEMBL7809459 | 0.75 | CA2 (0.34) | CA2GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107922537-B | Preparation of multiphase polymers in gas or slurry phase | 埃克森美孚化学专利公司 | 2021-07-27 | — | — | CN | disclosed |
| CN-1498231-A | Propylene polymer for films | ����ɭ���ڻ�ѧר����˾ | 2004-05-19 | — | — | CN | disclosed |
| EP-1263847-A1 | PROCESS FOR THE PREPARATION OF ADDITIVE COATED MOLDING POWDER | Borealis Technology Oy (FI) | 2002-12-11 | — | — | EP | disclosed |
| US-6407189-B1 | USING ORGANOMETALLIC COMPOUNDS AS CATALYST | CLARIANT GMBH (DE) | 2002-06-18 | — | — | US | disclosed |
| WO-2001062832-A1 | PROCESS FOR THE PREPARATION OF ADDITIVE COATED MOLDING POWDER | BOREALIS TECHNOLOGY OY (FI) | 2001-08-30 | — | — | WO | disclosed |
| EP-1123319-A2 | SUPPORTED POLYMERIZATION CATALYSTS | Borealis Technology (FI) | 2001-08-16 | — | — | EP | disclosed |
| US-20010007009-A1 | Transition metal catalyzed polymerization of olefinic monomers in a water-containing polymerization medium | BASF AKTIENGESELLSCHAFT (DE) | 2001-07-05 | — | — | US | disclosed |
| WO-2000022011-A2 | SUPPORTED POLYMERIZATION CATALYSTS | BOREALIS TECHNOLOGY OY (FI) | 2000-04-20 | — | — | WO | disclosed |
| CN-1246871-A | Propylene polymers incorporating polyethylene macromers | EXXON CHEMICAL PATENTS INC (US) | 2000-03-08 | — | — | CN | disclosed |