Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 4/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 4/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | WNT3 | P56703 | 2/20 | 0.35 |
| ▸ | SFRP1 | Q8N474 | 2/20 | 0.35 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.35 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5727851 | 0.76 | UCHL1 (0.41) | TSHRMEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL5730247 | 0.74 | GFER (0.45) | TSHRMEN1ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL5727924 | 0.73 | HSD11B1 (0.41) | MEN1ALDH1A1LMNAKMT2AL3MBTL1 | |
| SCHEMBL30308800 | 0.71 | TSHR (0.46) | TSHRMEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL29491244 | 0.71 | PRMT5 (0.55) | TSHRMEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL28814072 | 0.71 | PRMT5 (0.55) | TSHRMEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL29081662 | 0.70 | LMNA (0.46) | TSHRMEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL29331534 | 0.69 | ALDH1A1 (0.41) | TSHRMEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL24365782 | 0.69 | RIPK1 (0.63) | TSHRMEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL7469150 | 0.69 | RIPK1 (0.63) | TSHRMEN1ALDH1A1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020103377-A1 | Piperidinyloxy and pyrrolidinyloxy oxazolidinone antibacterials | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2002-08-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020103377-A1 | Piperidinyloxy and pyrrolidinyloxy oxazolidinone antibacterials | OXA1L, RPS27L, RPS27 | TSHR 3674/4885MEN1 3697/4885ALDH1A1 550/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.