Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN7 | P35236 | 1/20 | 0.39 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 4/20 | 0.38 |
| ▸ | TSPO | P30536 | 5/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8479514 | 0.92 | PARP1 (0.38) | CNR2TSPOPPARGPPARDPPARA | |
| SCHEMBL7612724 | 0.89 | ALDH1A1 (0.39) | PPARGPPARDPPARAKMT2AALDH1A1 | |
| SCHEMBL7609587 | 0.87 | KMT2A (0.46) | CNR2PPARGPPARDPPARAKMT2A | |
| SCHEMBL8476849 | 0.86 | OPRD1 (0.44) | PTPN7DUSP3CNR2TSPOOPRD1 | |
| SCHEMBL7613036 | 0.85 | KDM4E (0.38) | CNR2PPARGPPARDPPARAKMT2A | |
| SCHEMBL7616866 | 0.85 | PTGER4 (0.38) | PPARGPPARDPPARAKMT2AALDH1A1 | |
| SCHEMBL8472329 | 0.85 | EGFR (0.41) | KMT2AALDH1A1PTGER4 | |
| SCHEMBL7615347 | 0.83 | CNR2 (0.44) | CNR2PTGER4 | |
| SCHEMBL7618604 | 0.82 | HTR6 (0.35) | PTPN7DUSP3CNR2TSPOOPRD1 | |
| SCHEMBL7617024 | 0.82 | ALDH1A1 (0.38) | CNR2KMT2AALDH1A1PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0741132-B1 | INDOLE DERIVATIVES | KYOWA HAKKO KOGYO KK (JP) | 2002-04-10 | — | — | EP | disclosed |
| US-5891902-A | OSTEOPOROSIS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0741132-A1 | INDOLE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1996-11-06 | — | — | EP | disclosed |