Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | TSPO | P30536 | 4/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.32 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.32 |
| ▸ | WEE1 | P30291 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PER2 | O15055 | 1/20 | 0.32 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.32 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.32 |
| ▸ | TOP2A | P11388 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7618598 | 0.91 | HTR6 (0.38) | HTR6TSPOOPRD1CNR2HIF1A | |
| SCHEMBL7615055 | 0.86 | KDM4E (0.36) | HTR6CNR2PTGER4KMT2APER2 | |
| SCHEMBL7615359 | 0.86 | DNM1 (0.36) | HTR6HIF1APTGER4KMT2ASRC | |
| SCHEMBL7615408 | 0.84 | CNR2 (0.36) | HTR6CNR2PTGER4KMT2A | |
| SCHEMBL8476849 | 0.83 | OPRD1 (0.44) | HTR6TSPOOPRD1CNR2PTPN7 | |
| SCHEMBL7612504 | 0.82 | PTPN7 (0.39) | TSPOOPRD1CNR2PTPN7DUSP3 | |
| SCHEMBL8474836 | 0.82 | ENPP1 (0.37) | KMT2A | |
| SCHEMBL7614890 | 0.82 | KMT2A (0.37) | PTGER4KMT2A | |
| SCHEMBL8474349 | 0.82 | KMT2A (0.37) | PTGER4KMT2A | |
| SCHEMBL8473185 | 0.82 | TOP2A (0.38) | HTR6TSPOCNR2PTGER4UTS2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0741132-B1 | INDOLE DERIVATIVES | KYOWA HAKKO KOGYO KK (JP) | 2002-04-10 | — | — | EP | disclosed |
| US-5891902-A | OSTEOPOROSIS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0741132-A1 | INDOLE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1996-11-06 | — | — | EP | disclosed |