SCHEMBL76157

SCHEMBL76157

NC(=O)CCSSc1ccccn1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.55
EHMT2 Q96KQ7 1/20 0.50
EHMT1 Q9H9B1 1/20 0.50
APOBEC3G Q9HC16 1/20 0.50
KMT2A Q03164 2/20 0.48
MAPT P10636 1/20 0.48
MEN1 O00255 1/20 0.41
PKM P14618 1/20 0.41
RAB9A P51151 6/20 0.41
NPC1 O15118 5/20 0.41
SMN1; SMN2 Q16637 5/20 0.41
HPGD P15428 4/20 0.41
POLB P06746 3/20 0.40
LMNA P02545 1/20 0.40
HDAC1 Q13547 2/20 0.39
HDAC2 Q92769 2/20 0.39
HSD17B10 Q99714 2/20 0.39
KDM4E B2RXH2 1/20 0.39
ALOX15 P16050 1/20 0.39
TDP1 Q9NUW8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL21359817 0.95 ALDH1A1 (0.51) ALDH1A1EHMT2EHMT1APOBEC3GKMT2A
SCHEMBL4339779 0.94 ALDH1A1 (0.50) ALDH1A1EHMT2EHMT1APOBEC3GKMT2A
SCHEMBL15927528 0.92 ALDH1A1 (0.50) ALDH1A1EHMT2EHMT1APOBEC3GKMT2A
SCHEMBL8737870 0.91 ALDH1A1 (0.53) ALDH1A1EHMT2EHMT1APOBEC3GKMT2A
Hexanoate SCHEMBL30182683 0.87 ALDH1A1 (0.50) ALDH1A1EHMT2EHMT1APOBEC3GKMT2A
SCHEMBL98030 0.87 ALDH1A1 (0.73) ALDH1A1EHMT2EHMT1APOBEC3GKMT2A
SCHEMBL29811281 0.87 ALDH1A1 (0.73) ALDH1A1EHMT2EHMT1APOBEC3GKMT2A
SCHEMBL30308346 0.85 ALDH1A1 (0.71) ALDH1A1EHMT2EHMT1APOBEC3GKMT2A
SCHEMBL8681802 0.85 ALDH1A1 (0.57) ALDH1A1EHMT2EHMT1APOBEC3GKMT2A
SCHEMBL13739021 0.85 ALDH1A1 (0.57) ALDH1A1EHMT2EHMT1APOBEC3GKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1155 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11993618-B2 Water soluble mono-branched and di-branched complexing agents, and corresponding lanthanide complexes CISBIO BIOASSAYS (FR) 2024-05-28 US claimed
US-11939350-B2 Fluorescent dyes and methods of use thereof ENZO LIFE SCIENCES, INC. (US) 2024-03-26 US claimed
US-11649253-B2 Terbium and dysprosium complexes with optimised antenna, used as luminescent markers ECOLE NORMALE SUPERIEURE DE LYON (FR) 2023-05-16 US claimed
US-20230017272-A1 NEW WATER SOLUBLE MONO-BRANCHED AND DI-BRANCHED COMPLEXING AGENTS, AND CORRESPONDING LANTHANIDE COMPLEXES CISBIO BIOASSA YS (FR) 2023-01-19 US claimed
US-20210079034-A1 FLUORESCENT DYES AND METHODS OF USE THEREOF ENZO LIFE SCIENCES, INC. (US) 2021-03-18 US claimed
US-20210079225-A1 MONOAZO DYES WITH CYCLIC AMINE AS FLUORESCENCE QUENCHERS ENZO BIOCHEM, INC. (US) 2021-03-18 US claimed
EP-3649214-B1 TERBIUM AND DYSPROSIUM COMPLEXES WITH OPTIMISED ANTENNA, USED AS LUMINESCENT MARKERS ECOLE NORMALE SUPERIEURE LYON (FR) 2021-03-17 EP claimed
US-20210009809-A1 DYES FOR ANALYSIS OF PROTEIN AGGREGATION ENZO LIFE SCIENCES, INC. (US) 2021-01-14 US claimed
EP-3747877-A1 FLUORESCENT DYES Enzo Life Sciences, Inc., c/o Enzo Biochem, Inc. (US) 2020-12-09 EP claimed
US-20200223869-A1 TERBIUM AND DYSPROSIUM COMPLEXES WITH OPTIMISED ANTENNA, USED AS LUMINESCENT MARKERS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2020-07-16 US claimed
EP-1394219-A1 PH sensitive cyanine dyes as reactive fluorescent reagents CARNEGIE-MELLON UNIVERSITY (US) 2004-03-03 EP claimed
WO-2003104685-A2 FLUORESCENT ENTITY COMPRISING A FLUOROPHORE COVALENTLY ATTACHED TO AT LEAST ONE OLIGONUCLEOTIDE AND COMPRISING AT LEAST ONE FUNCTIONAL GROUP, AND USES THEREOF CIS BIO INTERNATIONAL (FR) 2003-12-18 WO claimed
US-20030225247-A1 Labeling reagents and labeled targets, target labeling processes and other processes for using same in nucleic acid determinations and analyses ENZO LIFE SCIENCES, INC. 2003-12-04 US claimed
EP-1212375-A2 PH SENSITIVE CYANINE DYES AS REACTIVE FLUORESCENT REAGENTS CARNEGIE-MELLON UNIVERSITY (US) 2002-06-12 EP claimed
WO-2000075237-A9 pH SENSITIVE CYANINE DYES AS REACTIVE FLUORESCENT REAGENTS UNIV CARNEGIE MELLON (US) 2002-05-10 WO claimed
WO-2000075237-A2 pH SENSITIVE CYANINE DYES AS REACTIVE FLUORESCENT REAGENTS CARNEGIE MELLON UNIVERSITY (US) 2000-12-14 WO claimed
EP-0769145-A1 N-HETEROAROMATIC ION AND IMINIUM ION SUBSTITUTED CYANINE DYES FOR USE AS FLUORESCENCE LABELS BIOMETRIC IMAGING INC. (US) 1997-04-23 EP claimed
US-5569587-A REACTING LIQUID CONTAINING PROTEINS, SUGARS, CELLS, NUCLEIC ACIDS WITH LUMINESCENT CYANINE, MEROCYANINE, AND STYRYL DYES CARNEGIE MELLON UNIVERSITY (US) 1996-10-29 US claimed
WO-1996000902-A1 N-HETEROAROMATIC ION AND IMINIUM ION SUBSTITUTED CYANINE DYES FOR USE AS FLUORESCENCE LABELS BIOMETRIC IMAGING, INC. (US) 1996-01-11 WO claimed
US-5453505-A Photostability, nonaggregating, DNA, cells, antibodies, carbohydrates BIOMETRIC IMAGING, INC. (US) 1995-09-26 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200223869-A1 TERBIUM AND DYSPROSIUM COMPLEXES WITH OPTIMISED ANTENNA, USED AS LUMINESCENT MARKERS TACR3, MAL2, SSB ALDH1A1 4265/4885EHMT2 4418/4885EHMT1 4590/4885
US-11993618-B2 Water soluble mono-branched and di-branched complexing agents, and corresponding lanthanide complexes LASP1, RCC1, LGALS1 ALDH1A1 3712/4885EHMT2 4539/4885EHMT1 4425/4885
US-20210009809-A1 DYES FOR ANALYSIS OF PROTEIN AGGREGATION CRYAA, CRYAB, HSPH1 ALDH1A1 2438/4885EHMT2 4780/4885EHMT1 4795/4885
US-20210079034-A1 FLUORESCENT DYES AND METHODS OF USE THEREOF BCDIN3D, EFTUD2, IK ALDH1A1 245/4885EHMT2 1031/4885EHMT1 1297/4885
US-11649253-B2 Terbium and dysprosium complexes with optimised antenna, used as luminescent markers SSB, TACR3, MAL2 ALDH1A1 4594/4885EHMT2 4636/4885EHMT1 4750/4885
US-20030225247-A1 Labeling reagents and labeled targets, target labeling processes and other processes for using same in nucleic acid determinations and analyses POLRMT, CHLSN, PHAX ALDH1A1 3587/4885EHMT2 3919/4885EHMT1 3987/4885
US-20230017272-A1 NEW WATER SOLUBLE MONO-BRANCHED AND DI-BRANCHED COMPLEXING AGENTS, AND CORRESPONDING LANTHANIDE COMPLEXES LASP1, RCC1, AQP1 ALDH1A1 3403/4885EHMT2 4605/4885EHMT1 4471/4885
US-11939350-B2 Fluorescent dyes and methods of use thereof BCDIN3D, EFTUD2, IK ALDH1A1 245/4885EHMT2 1031/4885EHMT1 1297/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.