SCHEMBL761683

SCHEMBL761683

CCC(=O)ON1CCCC1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P2RY12 Q9H244 6/20 0.34
L3MBTL1 Q9Y468 4/20 0.33
ALDH1A1 P00352 2/20 0.33
CHRM2 P08172 2/20 0.33
CHRM4 P08173 2/20 0.33
CHRM1 P11229 2/20 0.33
CHRM3 P20309 2/20 0.33
HPGD P15428 2/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2C19 P33261 1/20 0.32
BLM P54132 1/20 0.32
WRN Q14191 1/20 0.32
HIF1A Q16665 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
NAAA Q02083 1/20 0.31
KDM4E B2RXH2 1/20 0.31
MAPT P10636 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8429904 1.00 P2RY12 (0.34) P2RY12L3MBTL1ALDH1A1CHRM2CHRM4
SCHEMBL762068 0.98 L3MBTL1 (0.35) P2RY12L3MBTL1ALDH1A1CHRM2CHRM4
Hydrochloric Acid SCHEMBL27501009 0.96 L3MBTL1 (0.35) P2RY12L3MBTL1ALDH1A1HPGDCYP1A2
SCHEMBL30335967 0.95
Hydrochloric Acid SCHEMBL9615011 0.93 P2RY12 (0.33) P2RY12ALDH1A1CHRM2CHRM4CHRM1
SCHEMBL3790152 0.90
SCHEMBL8433432 0.82 ALDH1A1 (0.46) L3MBTL1ALDH1A1HPGDMEN1KMT2A
SCHEMBL6847340 0.82 HTR1A (0.39) P2RY12CYP1A2TDP1KDM4E
SCHEMBL220296 0.82 ALDH1A1 (0.46) L3MBTL1ALDH1A1HPGDMEN1KMT2A
SCHEMBL2963308 0.80 TSHR (0.46) L3MBTL1ALDH1A1HPGDCYP2C19KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119080615-A Method for preparing long-chain dibasic acid or dibasic ester 中国科学院大连化学物理研究所 2024-12-06 CN claimed
US-11851392-B2 Self-condensation of aldehydes EASTMAN CHEMICAL COMPANY (US) 2023-12-26 US claimed
EP-3880640-A1 SELF-CONDENSATION OF ALDEHYDES Eastman Chemical Company (US) 2021-09-22 EP claimed
CN-112955423-A Self-condensation of aldehydes 伊士曼化工公司 2021-06-11 CN claimed
WO-2020101902-A1 SELF-CONDENSATION OF ALDEHYDES EASTMAN CHEMICAL COMPANY (US) 2020-05-22 WO claimed
CN-119080615-A Method for preparing long-chain dibasic acid or dibasic ester 中国科学院大连化学物理研究所 2024-12-06 CN disclosed
CN-114477249-B Method for preparing high-purity magnesium hydroxide and calcium sulfate by adopting calcium carbide furnace purification ash 龙岩紫云化学科技有限公司 2024-01-30 CN disclosed
US-11851392-B2 Self-condensation of aldehydes EASTMAN CHEMICAL COMPANY (US) 2023-12-26 US disclosed
CN-111807403-B Extraction solution, application and method for preparing active light calcium carbonate and co-producing high-purity magnesium hydroxide and/or magnesium carbonate 厦门市汇创源科技有限公司 2022-09-23 CN disclosed
CN-114477249-A Method for preparing high-purity magnesium hydroxide and calcium sulfate by adopting calcium carbide furnace purification ash 龙岩紫云化学科技有限公司 2022-05-13 CN disclosed
US-20210380508-A1 SELF-CONDENSATION OF ALDEHYDES EASTMAN CHEMICAL COMPANY (US) 2021-12-09 US disclosed
EP-3880640-A1 SELF-CONDENSATION OF ALDEHYDES Eastman Chemical Company (US) 2021-09-22 EP disclosed
EP-0600717-A1 Phenoxyalkylamines, -pyrrolidines and -piperidines for the treatment and prevention of circulatory diseases and psychosis SANKYO COMPANY LIMITED (JP) 1994-06-08 EP disclosed
EP-0027948-B1 TETRAHYDRO-FLUORENE COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THEREOF MERCK & CO. INC. (US) 1984-03-21 EP disclosed
US-4356313-A [(5,6,9a-substituted-3-oxo-1,2,9,9a-tetrahydro-3H-fluoren-7-yl)oxy]alkanoic and cycloalkanoic acid esters and their analogs, the parent acids and their salts MERCK & CO., INC. (US) 1982-10-26 US disclosed
US-4356314-A [5,6,9A-Substituted-3-oxo-1,2,9,9a-tetrahydro-3H-fluoren-7-yl)oxy]alkanoic and cycloalkanoic acids, their analogs, esters, salts, and derivatives MERCK & CO., INC. (US) 1982-10-26 US disclosed
US-4337354-A BRAIN AND SPINAL CHORD DAMAGE MERCK & CO., INC. (US) 1982-06-29 US disclosed
US-4317922-A [(5,6,9a-Substituted-3-oxo-1,2,9,9a-tetrahydro-3H-fluoren-7-yl)oxy]alkanoic and cycloalkanoic acids and their analogs, esters, salts and derivatives MERCK & CO., INC. (US) 1982-03-02 US disclosed
US-4316043-A ANTIEDEMIC AGENTS MERCK & CO., INC. (US) 1982-02-16 US disclosed
EP-0027948-A1 Tetrahydro-fluorene compounds, processes for their preparation and pharmaceutical compositions thereof MERCK & CO. INC. (US) 1981-05-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11851392-B2 Self-condensation of aldehydes ALKBH2, DBF4, ALKBH3 P2RY12 3591/4885L3MBTL1 3769/4885ALDH1A1 61/4885
US-20210380508-A1 SELF-CONDENSATION OF ALDEHYDES ALKBH2, DBF4, ALKBH3 P2RY12 3591/4885L3MBTL1 3769/4885ALDH1A1 61/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.