Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.54 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.40 |
| ▸ | PTGIR | P43119 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3661402 | 0.87 | ALDH1A1 (0.60) | ALDH1A1ADRA2CCES2TSHRRORC | |
| SCHEMBL9716677 | 0.80 | ADRA2C (0.53) | ALDH1A1ADRA2CCES2TSHRESR1 | |
| SCHEMBL3656192 | 0.80 | ALDH1A1 (0.51) | ALDH1A1ADRA2CCES2TSHRESR1 | |
| SCHEMBL4190476 | 0.79 | ALDH1A1 (0.52) | ALDH1A1ADRA2CCES2TSHRRORC | |
| SCHEMBL11734968 | 0.78 | ALDH1A1 (0.48) | ALDH1A1ADRA2CTSHRESR1ESR2 | |
| SCHEMBL28827956 | 0.77 | ADRA2C (0.66) | ALDH1A1ADRA2CTSHRPOLBPTGIR | |
| SCHEMBL28637636 | 0.76 | TSHR (0.70) | ALDH1A1ADRA2CCES2TSHRRORC | |
| SCHEMBL6909286 | 0.76 | CA2 (0.42) | ALDH1A1TSHRESR1ESR2PDK1 | |
| SCHEMBL19240708 | 0.76 | RAB9A (0.55) | ALDH1A1ADRA2CMEN1KMT2ARAB9A | |
| SCHEMBL7624972 | 0.76 | LMNA (0.49) | ALDH1A1CHRM2CHRM3ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020061839-A1 | Serine peptidase modulators | SCHARPE SIMON LODEWIJK (BE) | 2002-05-23 | — | — | US | disclosed |
| EP-1062222-A1 | SERINE PEPTIDASE MODULATORS | Fondatech Benelux N.V. (BE) | 2000-12-27 | — | — | EP | disclosed |
| WO-1999046272-A1 | SERINE PEPTIDASE MODULATORS | FONDATECH BENELUX N.V. (BE) | 1999-09-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020061839-A1 | Serine peptidase modulators | FAP, CTSC, DPP4 | ALDH1A1 2096/4885ADRA2C 3856/4885CES2 1556/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.