SCHEMBL465814

SCHEMBL465814

O=c1ccsn1-c1ccc(OC(F)(F)F)cc1

nearest known ligand 0.53

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KAT2B Q92831 10/20 0.53
EP300 Q09472 5/20 0.53
IDO1 P14902 2/20 0.49
PIN1 Q13526 1/20 0.46
POLB P06746 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
MEN1 O00255 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2D6 P10635 1/20 0.39
MAPT P10636 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
KMT2A Q03164 1/20 0.39
KCNA5 P22460 1/20 0.39
PIM1 P11309 1/20 0.38
PIM2 Q9P1W9 1/20 0.38
EPHX2 P34913 1/20 0.38
ALDH1A1 P00352 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL465905 0.73 KAT2B (0.54) KAT2BPOLBL3MBTL1MEN1CYP1A2
SCHEMBL465941 0.70 MEN1 (0.43) KAT2BPOLBL3MBTL1MEN1CYP1A2
SCHEMBL254957 0.68 MAPT (0.56) L3MBTL1MEN1MAPTKMT2APIM1
SCHEMBL3006629 0.68 MGLL (0.58) POLBL3MBTL1MEN1CYP1A2CYP2D6
SCHEMBL10059454 0.68 MAPT (0.50) POLBL3MBTL1MEN1MAPTKMT2A
SCHEMBL24997232 0.67 POLB (0.59) POLBL3MBTL1MEN1CYP1A2CYP2D6
SCHEMBL21383412 0.67 L3MBTL1 (0.54) POLBL3MBTL1MEN1CYP1A2CYP2D6
SCHEMBL22864545 0.67 POLB (0.62) POLBL3MBTL1MEN1CYP1A2CYP2D6
SCHEMBL5265409 0.67 L3MBTL1 (0.47) POLBL3MBTL1MEN1CYP1A2CYP2D6
SCHEMBL16479476 0.66 TRPV1 (0.43) POLBL3MBTL1MEN1CYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2343975-B1 SPINOSYN ANTIFOULING COMPOSITIONS, METHODS OF USE THEREOF AND ARTICLES PROTECTED FROM ATTACHMENT OF BIOFOULING ORGANISMS ENTARCO SA (GR) 2012-09-12 EP claimed
US-7934888-B2 Marine anti-foulant system and methods for using same VIV SUPPRESSION, INC. (US) 2011-05-03 US claimed
US-20090185867-A1 MARINE ANTI-FOULANT SYSTEM AND METHODS FOR USING SAME ASSET INTEGRITY MANAGEMENT SOLUTIONS, L.L.C., D/B/A AIMS INTERNATIONAL 2009-07-23 US claimed
US-6610282-B1 Biologically active compounds that slowly release the biologically active compound. These compositions may be directly incorporated into the locus to be protected or may be applied to a structure in a coating. ROHM AND HAAS COMPANY 2003-08-26 US claimed
JP-7101948-A None JP disclosed
US-20130228096-A1 SPINOSYN ANTIFOULING COMPOSITIONS, METHODS OF USE THEREOF AND ARTICLES PROTECTED FROM ATTACHMENT OF BIOFOULING ORGANISMS ENTARCO SA (GR) 2013-09-05 US disclosed
US-20130195790-A1 SPINOSYN ANTIFOULING COMPOSITIONS, METHODS OF USE THEREOF AND ARTICLES PROTECTED FROM ATTACHMENT OF BIOFOULING ORGANISMS ENTARCO SA (GR) 2013-08-01 US disclosed
US-8470381-B2 Spinosyn antifouling compositions, methods of use thereof and articles protected from attachment of biofouling organisms Kritikou, Christine (GR) 2013-06-25 US disclosed
EP-2343975-B1 SPINOSYN ANTIFOULING COMPOSITIONS, METHODS OF USE THEREOF AND ARTICLES PROTECTED FROM ATTACHMENT OF BIOFOULING ORGANISMS ENTARCO SA (GR) 2012-09-12 EP disclosed
EP-2343975-A2 SPINOSYN ANTIFOULING COMPOSITIONS, METHODS OF USE THEREOF AND ARTICLES PROTECTED FROM ATTACHMENT OF BIOFOULING ORGANISMS Entarco SA (GR) 2011-07-20 EP disclosed
US-20110172173-A1 SPINOSYN ANTIFOULING COMPOSITIONS, METHODS OF USE THEREOF AND ARTICLES PROTECTED FROM ATTACHMENT OF BIOFOULING ORGANISMS CHRISTINE KRITIKOU (ONE-THIRD INTEREST) (GR) 2011-07-14 US disclosed
US-7934888-B2 Marine anti-foulant system and methods for using same VIV SUPPRESSION, INC. (US) 2011-05-03 US disclosed
EP-0835604-A1 Halopropargyl compounds as marine antifouling agents ROHM AND HAAS COMPANY (US) 1998-04-15 EP disclosed
EP-0659847-B1 Anti-fouling compositions and fouling control of harmful aquatic organisms CHUGOKU MARINE PAINTS (JP) 1998-03-18 EP disclosed
US-5683686-A Anti-fouling compositions comprising N-phenylisothiazalone derivatives and fouling control of harmful aquatic organisms using same CHUGOKU MARINE PAINTS, LTD. (JP) 1997-11-04 US disclosed
US-5663436-A Isothiazolone derivative and microbicidal composition comprising the same as active ingredient SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-09-02 US disclosed
US-5552423-A BACTERICIDE, FUNGICIDE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-09-03 US disclosed
EP-0659847-A1 Anti-fouling compositions and fouling control of harmful aquatic organisms Chugoku Marine Paints, Ltd. (JP) 1995-06-28 EP disclosed
EP-0648757-A1 Isothiazolone derivative and microbicidal composition comprising the same as active ingredient SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-04-19 EP disclosed
JP-H07101948-A ISOTHIAZOLONE DERIVATIVE AND INDUSTRIAL BACTERICIDE WITH THE SAME AS ACTIVE INGREDIENT SUMITOMO CHEM CO LTD 1995-04-18 JP disclosed