Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.34 |
| ▸ | HRH1 | P35367 | 2/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4978019 | 0.88 | ALDH1A1 (0.38) | KDM4ELMNAPOLBHPGDNPSR1 | |
| SCHEMBL7635398 | 0.76 | ALDH1A1 (0.39) | POLBALDH1A1CYP3A4CNR1CNR2 | |
| SCHEMBL4978016 | 0.69 | ALDH1A1 (0.41) | ALDH1A1CYP3A4CNR1CNR2RAB9A | |
| SCHEMBL8439467 | 0.68 | ALDH1A1 (0.36) | KDM4ELMNAPOLBHPGDNPSR1 | |
| SCHEMBL10371792 | 0.61 | ENPP2 (0.41) | KDM4ELMNAPOLBADRA1AHRH1 | |
| SCHEMBL23240258 | 0.61 | — | — | |
| SCHEMBL6975989 | 0.61 | RAB9A (0.59) | KDM4ELMNAALDH1A1CYP3A4RAB9A | |
| SCHEMBL7570871 | 0.59 | ALDH1A1 (0.36) | ALDH1A1CYP3A4HRH1RAB9APDE4D | |
| SCHEMBL2273652 | 0.59 | PSEN1 (0.49) | LMNAALDH1A1CYP3A4HRH1 | |
| SCHEMBL11296201 | 0.59 | HTR6 (0.41) | POLBALDH1A1HTR6ADCY10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6455468-B1 | CHOLINE CHLORIDE; A CALCIUM-CONTAINING SALT; A POTASSIUM-CONTAINING SALT; SALICYLIC ACID; GLYCEROL; CALCIUM NITRATE OR CALCIUM CHLORIDE, POTASSIUM NITRATE OR POTASSIUM CHLORIDE | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2002-09-24 | — | — | US | claimed |
| WO-2001082697-A2 | SEED TREATMENT COMPOSITION | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2001-11-08 | — | — | WO | claimed |
| US-6455468-B1 | CHOLINE CHLORIDE; A CALCIUM-CONTAINING SALT; A POTASSIUM-CONTAINING SALT; SALICYLIC ACID; GLYCEROL; CALCIUM NITRATE OR CALCIUM CHLORIDE, POTASSIUM NITRATE OR POTASSIUM CHLORIDE | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2002-09-24 | — | — | US | disclosed |