Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.50 |
| ▸ | NAT1 | P18440 | 1/20 | 0.50 |
| ▸ | HTR6 | P50406 | 4/20 | 0.47 |
| ▸ | AURKA | O14965 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5161585 | 0.93 | PTGS2 (0.54) | PTGS2PTGS1LMNANPSR1NAMPT | |
| SCHEMBL8844836 | 0.91 | HTR6 (0.55) | PTGS2NPSR1NAMPTHTR6HSD11B1 | |
| SCHEMBL250146 | 0.89 | PTGS2 (0.56) | PTGS2PTGS1NAMPTNAT1ALDH1A1 | |
| SCHEMBL9242466 | 0.87 | HTR6 (0.55) | PTGS2NAMPTHTR6HSD11B1KMT2A | |
| SCHEMBL7871346 | 0.86 | PTGS2 (0.56) | PTGS2PTGS1LMNANPSR1NAMPT | |
| SCHEMBL9840644 | 0.86 | KIF18A (0.51) | PTGS2PTGS1LMNANPSR1NAT1 | |
| SCHEMBL2947083 | 0.85 | ALDH1A1 (0.60) | PTGS2PTGS1NAMPTALDH1A1CYP3A4 | |
| SCHEMBL6899092 | 0.82 | POLB (0.54) | NAMPTHTR6HSD11B1KMT2AALOX5AP | |
| SCHEMBL9793431 | 0.80 | HTR6 (0.62) | NPSR1HTR6ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL7871344 | 0.80 | PTGS2 (0.49) | PTGS2PTGS1LMNANPSR1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6051720-A | Removal of contaminants from N-methyl-2-pyrrolidone | PHILLIPS PETROLEUM COMPANY (US) | 2000-04-18 | — | — | US | claimed |
| CN-108299363-B | A kind of synthetic method of 3- benzene sulfonyl class coumarin kind compound | 青岛农业大学 | 2019-10-08 | — | — | CN | disclosed |
| EP-1189884-A4 | REMOVAL OF CONTAMINANTS FROM N-METHYL-2-PYRROLIDONE | PHILLIPS PETROLEUM CO (US) | 2002-07-31 | — | — | EP | disclosed |
| EP-1189884-A1 | REMOVAL OF CONTAMINANTS FROM N-METHYL-2-PYRROLIDONE | Phillips Petroleum Company (US) | 2002-03-27 | — | — | EP | disclosed |
| WO-2000076965-A1 | REMOVAL OF CONTAMINANTS FROM N-METHYL-2-PYRROLIDONE | PHILLIPS PETROLEUM COMPANY (US) | 2000-12-21 | — | — | WO | disclosed |
| US-6051720-A | Removal of contaminants from N-methyl-2-pyrrolidone | PHILLIPS PETROLEUM COMPANY (US) | 2000-04-18 | — | — | US | disclosed |