Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5161585 | 0.87 | PTGS2 (0.54) | PTGS2PTGS1ALDH1A1CYP3A4MAPK1 | |
| SCHEMBL2947086 | 0.84 | PTGS2 (0.49) | PTGS2PTGS1ALDH1A1CYP3A4MAPK1 | |
| SCHEMBL7871346 | 0.84 | PTGS2 (0.56) | PTGS2PTGS1ALDH1A1CYP3A4MAPK1 | |
| SCHEMBL537547 | 0.83 | AKR1B1 (0.42) | PTGS2ALDH1A1MAPK1LMNAMAPT | |
| SCHEMBL7643603 | 0.80 | PTGS2 (0.54) | PTGS2PTGS1ALDH1A1CYP3A4MAPK1 | |
| SCHEMBL2947083 | 0.79 | ALDH1A1 (0.60) | PTGS2PTGS1ALDH1A1CYP3A4MAPK1 | |
| SCHEMBL1028866 | 0.78 | POLB (0.49) | PTGS2POLBKMT2AGAAMMP1 | |
| SCHEMBL9599324 | 0.78 | HTR6 (0.42) | PTGS2ALDH1A1POLBMAPTKMT2A | |
| SCHEMBL2019763 | 0.78 | KIF18A (0.55) | PTGS2PTGS1ALDH1A1CYP3A4MAPK1 | |
| SCHEMBL10869745 | 0.77 | ALDH1A1 (0.68) | PTGS2PTGS1ALDH1A1CYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112301-A1 | ION-EXCHANGE POLYMERS | VICTREX MANUFACTURING LIMITED (GB) | 2001-07-04 | — | — | EP | disclosed |
| WO-2000015691-A1 | ION-EXCHANGE POLYMERS | VICTREX MANUFACTURING LIMITED (GB) | 2000-03-23 | — | — | WO | disclosed |