Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PRKCI | P41743 | 1/20 | 0.43 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7659381 | 0.86 | KDM4E (0.49) | RAB9ANPC1TP53ALDH1A1KDM4E | |
| SCHEMBL7657293 | 0.82 | UCHL1 (0.46) | RAB9ANPC1LMNAKMT2AGAA | |
| Hydrochloric Acid SCHEMBL7655814 | 0.79 | FYN (0.50) | RAB9ANPC1TP53ALDH1A1KDM4E | |
| SCHEMBL7652092 | 0.77 | ALDH1A1 (0.50) | TP53ALDH1A1KDM4EPOLBHPGD | |
| SCHEMBL7652482 | 0.76 | CHEK2 (0.47) | RAB9ANPC1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL7663316 | 0.75 | GABRA1 (0.45) | RAB9ANPC1HPGD | |
| SCHEMBL7662205 | 0.72 | SIRT2 (0.53) | RAB9ANPC1TP53ALDH1A1KDM4E | |
| SCHEMBL8081307 | 0.69 | KDM4E (0.40) | RAB9ANPC1TP53ALDH1A1KDM4E | |
| SCHEMBL7662979 | 0.69 | NPC1 (0.60) | RAB9ANPC1TP53ALDH1A1KDM4E | |
| SCHEMBL7656725 | 0.68 | NR4A2 (0.45) | RAB9ANPC1ALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6340704-B1 | TREATING NERVE DISEASE OR BONE/JOINT DISEASE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-01-22 | — | — | US | disclosed |