Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UCHL1 | P09936 | 1/20 | 0.46 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | GAPDH | P04406 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | PLK4 | O00444 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7652092 | 0.85 | ALDH1A1 (0.50) | MEN1GAAKMT2AADORA3ADORA1 | |
| SCHEMBL7659381 | 0.84 | KDM4E (0.49) | MEN1LMNAKMT2ANPC1RAB9A | |
| SCHEMBL7652482 | 0.84 | CHEK2 (0.47) | GABRA1GABRB2GAPDHPRKD3CSNK1D | |
| SCHEMBL7663316 | 0.84 | GABRA1 (0.45) | ADORA3ADORA1ADORA2AGABRA1GABRB2 | |
| SCHEMBL7652598 | 0.82 | UCHL1 (0.48) | UCHL1USP30MEN1LMNAGAA | |
| SCHEMBL7652504 | 0.82 | RAB9A (0.54) | LMNAGAAKMT2ANPC1RAB9A | |
| Hydrochloric Acid SCHEMBL7655814 | 0.81 | FYN (0.50) | MEN1KMT2AFYNRETKDR | |
| SCHEMBL7662426 | 0.81 | ADORA3 (0.43) | MEN1GAAKMT2AADORA3ADORA1 | |
| SCHEMBL2954675 | 0.76 | FABP3 (0.40) | MEN1LMNAGAAKMT2AADORA3 | |
| SCHEMBL6913771 | 0.75 | ALOX5 (0.48) | MEN1LMNAGAAKMT2AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6340704-B1 | TREATING NERVE DISEASE OR BONE/JOINT DISEASE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-01-22 | — | — | US | disclosed |