Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 7/20 | 0.40 |
| ▸ | RAB9A | P51151 | 7/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7652504 | 0.86 | RAB9A (0.54) | KDM4EALDH1A1NPC1RAB9ATSHR | |
| SCHEMBL7657293 | 0.84 | UCHL1 (0.46) | NPC1RAB9ALMNAMEN1KMT2A | |
| SCHEMBL7652092 | 0.84 | ALDH1A1 (0.50) | KDM4EMAPK1ALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7655814 | 0.81 | FYN (0.50) | KDM4EALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL7652482 | 0.81 | CHEK2 (0.47) | KDM4EMAPK1ALDH1A1NPC1RAB9A | |
| SCHEMBL7663316 | 0.78 | GABRA1 (0.45) | NPC1RAB9AHPGD | |
| SCHEMBL1599746 | 0.75 | MAPK1 (0.83) | KDM4EMAPK1ALDH1A1NPC1RAB9A | |
| SCHEMBL2788308 | 0.75 | MAPK1 (0.83) | KDM4EMAPK1ALDH1A1NPC1RAB9A | |
| SCHEMBL27817050 | 0.74 | MAPK1 (0.81) | KDM4EMAPK1ALDH1A1NPC1RAB9A | |
| SCHEMBL494360 | 0.71 | TSHR (0.53) | KDM4EMAPK1ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6340704-B1 | TREATING NERVE DISEASE OR BONE/JOINT DISEASE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-01-22 | — | — | US | disclosed |