Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 5/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 2/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7652092 | 0.89 | ALDH1A1 (0.50) | TGFBR1ALDH1A1MAPK1KDM4EHPGD | |
| SCHEMBL7659425 | 0.85 | PLAU (0.44) | CHEK2PARP1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7657293 | 0.84 | UCHL1 (0.46) | NPC1RAB9APLAUPRKD3CSNK1D | |
| SCHEMBL7663316 | 0.84 | GABRA1 (0.45) | NPC1RAB9AHPGDGAPDHGABRA1 | |
| SCHEMBL25427368 | 0.83 | CHEK2 (0.52) | CHEK2PARP1PI4K2ANPC1RAB9A | |
| SCHEMBL7662193 | 0.82 | ABL1 (0.44) | CHEK2SMN1; SMN2CHEK1 | |
| Hydrochloric Acid SCHEMBL30589947 | 0.82 | CHEK2 (0.51) | CHEK2PARP1PI4K2ANPC1RAB9A | |
| SCHEMBL7659381 | 0.81 | KDM4E (0.49) | NPC1RAB9ASMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL7663095 | 0.81 | CHEK2 (0.53) | CHEK2PARP1PI4K2ANPC1RAB9A | |
| SCHEMBL7652504 | 0.76 | RAB9A (0.54) | NPC1RAB9ASMN1; SMN2TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6340704-B1 | TREATING NERVE DISEASE OR BONE/JOINT DISEASE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-01-22 | — | — | US | disclosed |