Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA4 | P22748 | 3/20 | 0.42 |
| ▸ | CA7 | P43166 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylamine SCHEMBL7652927 | 0.87 | MAPK14 (0.50) | ALDH1A1ADORA3ADORA2AADORA1RAB9A | |
| Dimethylamine SCHEMBL7649217 | 0.86 | ALDH1A1 (0.45) | ALDH1A1ADORA2AADORA1GAARAB9A | |
| Dimethylamine SCHEMBL7652490 | 0.85 | DHODH (0.52) | ADORA3ADORA2AADORA1ROCK2POLB | |
| SCHEMBL7652889 | 0.82 | CTSK (0.45) | ALDH1A1NPSR1ADORA3ADORA2AADORA1 | |
| SCHEMBL7656264 | 0.80 | ALDH1A1 (0.61) | ALDH1A1NPSR1ADORA3ADORA2AADORA1 | |
| Dimethylamine SCHEMBL7656702 | 0.79 | ADORA3 (0.48) | ALDH1A1ADORA3ADORA2AADORA1LMNA | |
| Dimethylamine SCHEMBL7679157 | 0.76 | ALDH1A1 (0.48) | ALDH1A1RAB9ALMNAKDM4EMEN1 | |
| Dimethylamine SCHEMBL7658435 | 0.75 | ALDH1A1 (0.44) | ALDH1A1KDM4EPOLB | |
| Dimethylamine SCHEMBL7656109 | 0.75 | OPRM1 (0.38) | ALDH1A1ADORA3ADORA2AADORA1GAA | |
| Dimethylamine SCHEMBL7655386 | 0.74 | ADORA2B (0.43) | ALDH1A1ADORA3ADORA2AADORA1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492407-B2 | NEUROPROTECTIVE ACTIVITY | BOEHRINGER IMGELHEIM PHARMA KG (DE) | 2002-12-10 | — | — | US | disclosed |