Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.42 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | FABP3 | P05413 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylamine SCHEMBL7658435 | 0.85 | ALDH1A1 (0.44) | ALDH1A1KDM4EDHODHTSHR | |
| Dimethylamine SCHEMBL7656109 | 0.85 | OPRM1 (0.38) | ADORA3ADORA1ADORA2AALDH1A1KDM4E | |
| Dimethylamine SCHEMBL7653735 | 0.82 | ALDH1A1 (0.44) | ALDH1A1DHODH | |
| Dimethylamine SCHEMBL7652266 | 0.82 | MAPK14 (0.42) | DHODHMEN1KMT2A | |
| SCHEMBL7656700 | 0.81 | ADORA3 (0.47) | ADORA3ADORA1ADORA2AAVPR2AVPR1A | |
| SCHEMBL7656052 | 0.79 | ADORA1 (0.54) | ADORA3ADORA1ADORA2AAVPR2AVPR1A | |
| Dimethylamine SCHEMBL7652894 | 0.79 | ALDH1A1 (0.48) | ADORA3ADORA1ADORA2AALDH1A1L3MBTL1 | |
| Dimethylamine SCHEMBL7652932 | 0.76 | L3MBTL1 (0.42) | ADORA3ALDH1A1L3MBTL1KDM4ELMNA | |
| Dimethylamine SCHEMBL7655386 | 0.76 | ADORA2B (0.43) | ADORA3ADORA1ADORA2AALDH1A1KDM4E | |
| Dimethylamine SCHEMBL7652927 | 0.74 | MAPK14 (0.50) | ADORA3ADORA1ADORA2AALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492407-B2 | NEUROPROTECTIVE ACTIVITY | BOEHRINGER IMGELHEIM PHARMA KG (DE) | 2002-12-10 | — | — | US | disclosed |