SCHEMBL765486

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9261774	0.89	AKR1C3 (0.53)	CYP2C19APPCYP2C9CYP3A4AKR1C3
	SCHEMBL29020110	0.86	APP (0.64)	CYP2C19APPCYP2C9CYP3A4AKR1C3
	SCHEMBL12570868	0.85	AKR1C3 (0.50)	CYP2C19APPCYP2C9CYP3A4AKR1C3
	SCHEMBL9285170	0.84	LMNA (0.51)	CYP2C19APPCYP2C9CYP3A4AKR1C3
	SCHEMBL10593081	0.83	TRPA1 (0.53)	CYP2C19APPCYP2C9CYP3A4PTGS1
	SCHEMBL29634557	0.83	LMNA (0.50)	CYP2C19APPCYP2C9CYP3A4PTGS1
	SCHEMBL2868070	0.83	LMNA (0.50)	CYP2C19APPCYP2C9CYP3A4PTGS1
	4'-Hydroxyflurbiprofen SCHEMBL7040151	0.82	APP (0.97)	CYP2C19APPCYP2C9CYP3A4AKR1C3
	4'-Hydroxyflurbiprofen SCHEMBL6450842	0.82	APP (0.97)	CYP2C19APPCYP2C9CYP3A4AKR1C3
	SCHEMBL17524312	0.82	APP (0.81)	CYP2C19APPCYP2C9CYP3A4AKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.