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SCHEMBL765992

SCHEMBL765992

COCCOc1ccc(/C=C/C(=O)N2CCCCC2)c(OC(=O)OC(C)(C)C)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HPGD P15428 2/20 0.46
▸ PTGS2 P35354 2/20 0.44
▸ KDM4E B2RXH2 3/20 0.41
▸ SMN1; SMN2 Q16637 2/20 0.41
▸ LMNA P02545 1/20 0.41
▸ GAA P10253 1/20 0.41
▸ TRPV1 Q8NER1 1/20 0.41
▸ ALDH1A1 P00352 3/20 0.40
▸ KMT2A Q03164 2/20 0.40
▸ PELI1 Q96FA3 2/20 0.40
▸ APP P05067 2/20 0.39
▸ HDAC8 Q9BY41 1/20 0.39
▸ NPC1 O15118 2/20 0.39
▸ RAB9A P51151 2/20 0.39
▸ MEN1 O00255 1/20 0.39
▸ MAPT P10636 1/20 0.39
▸ BCHE P06276 2/20 0.39
▸ MAOA P21397 2/20 0.39
▸ ACHE P22303 2/20 0.39
▸ MAOB P27338 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13087151 0.89 HPGD (0.53) HPGDPTGS2KDM4ESMN1; SMN2LMNA
SCHEMBL766030 0.83 HPGD (0.49) HPGDPTGS2KDM4ESMN1; SMN2TRPV1
SCHEMBL766006 0.83 PELI1 (0.56) HPGDPTGS2KDM4ESMN1; SMN2TRPV1
SCHEMBL766034 0.80 PELI1 (0.52) HPGDPTGS2KDM4ETRPV1ALDH1A1
SCHEMBL10227977 0.79 HPGD (0.53) HPGDPTGS2KDM4ESMN1; SMN2TRPV1
SCHEMBL766028 0.79 HPGD (0.65) HPGDKDM4ESMN1; SMN2TRPV1ALDH1A1
SCHEMBL20109837 0.79 PELI1 (0.50) HPGDPTGS2KDM4ESMN1; SMN2TRPV1
SCHEMBL766044 0.78 HPGD (0.45) HPGDPTGS2KDM4ESMN1; SMN2TRPV1
SCHEMBL13087048 0.78 TRPV1 (0.47) HPGDPTGS2KDM4ESMN1; SMN2TRPV1
SCHEMBL766038 0.78 ALDH1A1 (0.47) HPGDPTGS2KDM4ESMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120070781-A1 BASE GENERATOR, PHOTOSENSITIVE RESIN COMPOSITION, PATTERN FORMING MATERIAL COMPRISING THE PHOTOSENSITIVE RESIN COMPOSITION, PATTERN FORMING METHOD USING THE PHOTOSENSITIVE RESIN COMPOSITION AND PRODUCTS COMPRISING THE SAME DAI NIPPON PRINTING CO., LTD. (JP) 2012-03-22 — — US disclosed
US-20120070781-A1 BASE GENERATOR, PHOTOSENSITIVE RESIN COMPOSITION, PATTERN FORMING MATERIAL COMPRISING THE PHOTOSENSITIVE RESIN COMPOSITION, PATTERN FORMING METHOD USING THE PHOTOSENSITIVE RESIN COMPOSITION AND PRODUCTS COMPRISING THE SAME DAI NIPPON PRINTING CO., LTD. (JP) 2012-03-22 — — US disclosed
WO-2010113813-A1 BASE-GENERATING AGENT, PHOTOSENSITIVE RESIN COMPOSITION, PATTERNING MATERIAL COMPRISING THE PHOTOSENSITIVE RESIN COMPOSITION, PATTERNING METHOD AND ARTICLE USING THE PHOTOSENSITIVE RESIN COMPOSITION 大日本印刷株式会社 (JP) 2010-10-07 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120070781-A1 BASE GENERATOR, PHOTOSENSITIVE RESIN COMPOSITION, PATTERN FORMING MATERIAL COMPRISING THE PHOTOSENSITIVE RESIN COMPOSITION, PATTERN FORMING METHOD USING THE PHOTOSENSITIVE RESIN COMPOSITION AND PRODUCTS COMPRISING THE SAME RER1, SUN2, REV1 HPGD 861/4885PTGS2 1060/4885KDM4E 2434/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.