SCHEMBL509095

SCHEMBL509095

C=C(C)C1=NC(C)(c2ccccc2)C(=O)O1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.33
HCAR2 Q8TDS4 2/20 0.33
HCAR3 P49019 1/20 0.33
BACE1 P56817 3/20 0.32
CHRNB2 P17787 1/20 0.32
SLC6A2 P23975 1/20 0.32
CHRNB4 P30926 1/20 0.32
CHRNA3 P32297 1/20 0.32
CHRNA4 P43681 1/20 0.32
SLC6A3 Q01959 1/20 0.32
MMP2 P08253 1/20 0.32
MMP9 P14780 1/20 0.32
ALDH1A1 P00352 2/20 0.31
GAA P10253 1/20 0.31
HSD11B1 P28845 2/20 0.31
REN P00797 1/20 0.30
APP P05067 1/20 0.30
BACE2 Q9Y5Z0 1/20 0.30
CHRM2 P08172 1/20 0.30
CHRM4 P08173 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL508522 0.83 BACE1 (0.37) CYP1A2HCAR2HCAR3BACE1REN
SCHEMBL7662936 0.76 MMP2 (0.37) CYP1A2HCAR2HCAR3BACE1MMP2
SCHEMBL508332 0.76 ELANE (0.36) BACE1ALDH1A1GAA
SCHEMBL3969972 0.73 BACE1 (0.33) CYP1A2HCAR2HCAR3BACE1MMP2
SCHEMBL11245064 0.65 LMNA (0.38) CYP1A2BACE1CHRNB2SLC6A2CHRNB4
SCHEMBL509164 0.64 ALDH1A1 (0.34) ALDH1A1
SCHEMBL9557297 0.62 CHRNB2 (0.41) CYP1A2HCAR2HCAR3BACE1CHRNB2
SCHEMBL8209492 0.62 CTSD (0.37) CYP1A2BACE1CHRNB2SLC6A2CHRNB4
SCHEMBL6827479 0.60 BACE1 (0.43) BACE1MMP2MMP9RENAPP
SCHEMBL28548234 0.59 HCAR2 (0.53) CYP1A2HCAR2HCAR3MMP2MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 299 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12285922-B2 Method for making photofunctional contact lenses ALCON INC. (CH) 2025-04-29 US claimed
US-12111443-B2 Method for making photochromic contact lenses ALCON INC. (CH) 2024-10-08 US claimed
EP-4313567-A1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES Alcon Inc. (CH) 2024-02-07 EP claimed
EP-4304843-A1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES Alcon Inc. (CH) 2024-01-17 EP claimed
EP-4304842-A1 METHOD FOR MAKING PHOTOFUNCTIONAL CONTACT LENSES Alcon Inc. (CH) 2024-01-17 EP claimed
US-11833771-B2 Method for making photochromic contact lenses ALCON INC. (CH) 2023-12-05 US claimed
EP-3976362-B1 METHOD FOR MAKING OPAQUE COLORED SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2023-06-07 EP claimed
EP-4158392-A1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES Alcon Inc. (CH) 2023-04-05 EP claimed
US-11584097-B2 Method for making opaque colored silicone hydrogel contact lenses ALCON INC. (CH) 2023-02-21 US claimed
US-20220339895-A1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES ALCON INC. (CH) 2022-10-27 US claimed
EP-0413551-B1 Stabilized polymeric dispersions MINNESOTA MINING & MFG (US) 1995-05-24 EP claimed
US-5408002-A Blending with thermoplastic polymers; medical diagnostic equipment MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-04-18 US claimed
WO-1995007317-A2 AZLACTONE-FUNCTIONAL POLYMER BLENDS, ARTICLES PRODUCED THEREFROM AND METHODS FOR PREPARING BOTH MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-03-16 WO claimed
WO-1993025594-A1 SUPPORTS HAVING AZLACTONE-FUNCTIONAL SURFACES, ADDUCT SUPPORTS, AND METHODS OF PREPARING SAME MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-12-23 WO claimed
US-5262484-A Free radical grafting to addition polymers; surface treatment with nucleophilic agents; adhesion properties for binding, immobilizing proteins; immunoassay MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-11-16 US claimed
US-5075352-A Stabilized polymeric dispersions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-12-24 US claimed
US-5013795-A Azlactone graft copolymers MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-05-07 US claimed
EP-0413551-A2 Stabilized polymeric dispersions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-02-20 EP claimed
US-4451619-A COPOLYMERIZING AN ALKENYLAZLACTONE, RING OPENING WITH NUCLEOPHILE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1984-05-29 US claimed
EP-0105666-A1 Method of hydrophilizing or hydrophobizing polymers MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1984-04-18 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11584097-B2 Method for making opaque colored silicone hydrogel contact lenses COIL, CRYAB, CRYAA CYP1A2 1655/4885HCAR2 3193/4885HCAR3 1819/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.