Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLA1 | P09884 | 1/20 | 0.73 |
| ▸ | CYP46A1 | Q9Y6A2 | 2/20 | 0.69 |
| ▸ | OSBP | P22059 | 3/20 | 0.65 |
| ▸ | USP2 | O75604 | 2/20 | 0.65 |
| ▸ | RORC | P51449 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.65 |
| ▸ | OSBP2 | Q969R2 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.58 |
| ▸ | NPC1L1 | Q9UHC9 | 2/20 | 0.57 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.56 |
| ▸ | GBA1 | P04062 | 2/20 | 0.56 |
| ▸ | UGCG | Q16739 | 2/20 | 0.56 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.56 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.56 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.56 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL246635 | 1.00 | POLA1 (0.73) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL246636 | 1.00 | POLA1 (0.73) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL11563103 | 0.94 | POLA1 (0.65) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL11563100 | 0.94 | POLA1 (0.65) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL12290965 | 0.94 | POLA1 (0.69) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL137969 | 0.92 | POLA1 (0.79) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL6419070 | 0.92 | POLA1 (0.79) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL25352991 | 0.92 | POLA1 (0.66) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL8097151 | 0.92 | POLA1 (0.66) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL2565939 | 0.92 | POLA1 (0.66) | POLA1CYP46A1OSBPUSP2RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10029127-B2 | Anhydrous antisun cream comprising a non-emulsifying elastomeric organopolysiloxane, a matting agent and a non-silicone organic oil thickener | L'OREAL (FR) | 2018-07-24 | — | — | US | disclosed |
| US-8980240-B2 | Eyelash makeup and/or care assembly | L'OREAL (FR) | 2015-03-17 | — | — | US | disclosed |
| US-20140178317-A1 | ANHYDROUS ANTISUN CREAM COMPRISING A NON-EMULSIFYING ELASTOMERIC ORGANOPOLYSILOXANE, A MATTING AGENT AND A NON-SILICONE ORGANIC OIL THICKENER | L'OREAL (FR) | 2014-06-26 | — | — | US | disclosed |
| US-8404794-B2 | Liquid crystal compositions | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-03-26 | — | — | US | disclosed |
| US-8344175-B2 | Liquid crystal compositions, polymer networks derived therefrom and process for making the same | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-01-01 | — | — | US | disclosed |
| WO-2012168102-A2 | ANHYDROUS ANTISUN CREAM COMPRISING A NON-EMULSIFYING ELASTOMERIC ORGANOPOLYSILOXANE, A MATTING AGENT AND A NON-SILICONE ORGANIC OIL THICKENER | L'OREAL (FR) | 2012-12-13 | — | — | WO | disclosed |
| US-20120104316-A1 | LIQUID CRYSTAL COMPOSITIONS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-05-03 | — | — | US | disclosed |
| EP-2440632-A2 | LIQUID CRYSTAL COMPOSITIONS | E. I. du Pont de Nemours and Company (US) | 2012-04-18 | — | — | EP | disclosed |
| EP-2440631-A1 | LIQUID CRYSTAL COMPOSITIONS | E. I. du Pont de Nemours and Company (US) | 2012-04-18 | — | — | EP | disclosed |
| US-20120071618-A1 | LIQUID CRYSTAL COMPOSITIONS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-03-22 | — | — | US | disclosed |
| US-20100308270-A1 | LIQUID CRYSTAL COMPOSTIONS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-12-09 | — | — | US | disclosed |
| US-20100308268-A1 | LIQUID CRYSTAL COMPOSITIONS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-12-09 | — | — | US | disclosed |
| US-20100308265-A1 | LIQUID CRYSTAL COMPOSITIONS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-12-09 | — | — | US | disclosed |
| US-20100308269-A1 | LIQUID CRYSTAL COMPOSITIONS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-12-09 | — | — | US | disclosed |
| US-20100031969-A1 | EYELASH MAKEUP AND/OR CARE ASSEMBLY | L'OREAL (FR) | 2010-02-11 | — | — | US | disclosed |
| CN-101415797-A | Liquid crystal compositions, polymer networks derived therefrom and process for making the same | DU PONT (US) | 2009-04-22 | — | — | CN | disclosed |
| EP-2001974-A1 | LIQUID CRYSTAL COMPOSITIONS, POLYMER NETWORKS DERIVED THEREFROM AND PROCESS FOR MAKING THE SAME | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-12-17 | — | — | EP | disclosed |
| WO-2007120458-A1 | LIQUID CRYSTAL COMPOSITIONS, POLYMER NETWORKS DERIVED THEREFROM AND PROCESS FOR MAKING THE SAME | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-10-25 | — | — | WO | disclosed |
| US-20070228326-A1 | Liquid crystal compositions, polymer networks derived therefrom and process for making the same | E. I. DU PONT DE NEMOURS AND COMPANY | 2007-10-04 | — | — | US | disclosed |
| US-4140016-A | CHOLESTERIC LIQUID CRYSTAL THERMOMETERS, BENZOIC ESTER DERIVATIVES | BECTON, DICKINSON AND COMPANY (US) | 1979-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100308265-A1 | LIQUID CRYSTAL COMPOSITIONS | CNOT9, AQP3, AQP1 | POLA1 1326/4885CYP46A1 2900/4885OSBP 3849/4885 |
| US-20100308270-A1 | LIQUID CRYSTAL COMPOSTIONS | TTR, CNOT9, CNOT7 | POLA1 570/4885CYP46A1 756/4885OSBP 3668/4885 |
| US-20100031969-A1 | EYELASH MAKEUP AND/OR CARE ASSEMBLY | KRT18, FLNA, F7 | POLA1 1163/4885CYP46A1 3279/4885OSBP 772/4885 |
| US-10029127-B2 | Anhydrous antisun cream comprising a non-emulsifying elastomeric organopolysiloxane, a matting agent and a non-silicone organic oil thickener | CUTA, AUP1, DDOST | POLA1 655/4885CYP46A1 245/4885OSBP 35/4885 |
| US-20140178317-A1 | ANHYDROUS ANTISUN CREAM COMPRISING A NON-EMULSIFYING ELASTOMERIC ORGANOPOLYSILOXANE, A MATTING AGENT AND A NON-SILICONE ORGANIC OIL THICKENER | CUTA, AUP1, DDOST | POLA1 655/4885CYP46A1 245/4885OSBP 35/4885 |
| US-20120071618-A1 | LIQUID CRYSTAL COMPOSITIONS | CNOT9, AQP3, AQP1 | POLA1 1326/4885CYP46A1 2900/4885OSBP 3849/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.