Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 10/20 | 0.53 |
| ▸ | HTR7 | P34969 | 7/20 | 0.53 |
| ▸ | DRD2 | P14416 | 5/20 | 0.53 |
| ▸ | HTR2A | P28223 | 5/20 | 0.53 |
| ▸ | HTR6 | P50406 | 2/20 | 0.53 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7677803 | 0.87 | HTR7 (0.51) | HTR1AHTR7DRD2HTR2AHTR6 | |
| SCHEMBL7679781 | 0.86 | HTR1A (0.50) | HTR1AHTR7DRD2HTR2AHTR6 | |
| SCHEMBL7686952 | 0.85 | ALDH1A1 (0.51) | DRD2ADRA1DADRA1AADRA1BDRD3 | |
| SCHEMBL7677052 | 0.85 | HTR1A (0.44) | HTR1AHTR7DRD2HTR2AHTR6 | |
| SCHEMBL7685522 | 0.83 | HTR7 (0.48) | HTR1AHTR7DRD2ADRA1DADRA1A | |
| SCHEMBL7683742 | 0.82 | DRD2 (0.48) | HTR1AHTR7DRD2HTR2AHTR6 | |
| SCHEMBL7683519 | 0.81 | DRD2 (0.43) | HTR1AHTR7DRD2HTR2AHTR6 | |
| SCHEMBL7686165 | 0.81 | HTR7 (0.54) | HTR1AHTR7DRD2HTR2AHTR6 | |
| SCHEMBL7681793 | 0.80 | HTR1A (0.47) | HTR1AHTR7DRD2HTR2AHTR6 | |
| SCHEMBL7686977 | 0.80 | HTR1A (0.47) | HTR1AHTR7DRD2HTR2AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6346622-B1 | ENANTIOMORPHS AND ISOMERS | ABBOTT LABORATORIES | 2002-02-12 | — | — | US | disclosed |