Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 4/20 | 0.48 |
| ▸ | HTR1A | P08908 | 5/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 7/20 | 0.45 |
| ▸ | DRD4 | P21917 | 4/20 | 0.42 |
| ▸ | HTR1B | P28222 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7686952 | 0.83 | ALDH1A1 (0.51) | ADRA1AADRA1BADRA1DDRD2DRD3 | |
| SCHEMBL7687016 | 0.83 | HTR1A (0.53) | HTR7HTR1AADRA1AADRA1BADRA1D | |
| SCHEMBL7683519 | 0.81 | DRD2 (0.43) | HTR7HTR1AADRA1AADRA1BADRA1D | |
| SCHEMBL7682473 | 0.76 | HTR1A (0.54) | HTR7HTR1ADRD2DRD4 | |
| SCHEMBL7686993 | 0.76 | DRD2 (0.46) | HTR7HTR1ADRD2DRD4DRD3 | |
| SCHEMBL7684659 | 0.74 | MEN1 (0.54) | HTR1AADRA1AADRA1BDRD2DRD4 | |
| SCHEMBL7675521 | 0.73 | HRH4 (0.54) | HTR1AADRA1AADRA1BADRA1DDRD2 | |
| SCHEMBL7686048 | 0.73 | HTR7 (0.42) | HTR7HTR1ADRD2 | |
| SCHEMBL7683751 | 0.72 | HTR1A (0.57) | HTR7HTR1AADRA1AADRA1BADRA1D | |
| SCHEMBL7677803 | 0.70 | HTR7 (0.51) | HTR7HTR1AADRA1AADRA1BADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6346622-B1 | ENANTIOMORPHS AND ISOMERS | ABBOTT LABORATORIES | 2002-02-12 | — | — | US | disclosed |